Recombinant alpha-Synuclein Protein, Human Recombinant Proteins The mature form of human SNCA isoform 1 (P37840-1) (Met 1-Ala 140) was expressed and purified The recombinant human SNCA consisting of 140a.a and has a calculated molecular weight of 14.5 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human SNCA consisting of 140a.a and has a calculated molecular weight of 14.5 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant alpha-Synuclein Protein, Human

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-204711

Molecular Weight: The recombinant human SNCA consisting of 140a.a and has a calculated molecular weight of 14.5 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions.

Formulation: Recombinant alpha-Synuclein Protein was lyophilized from sterile PBS, pH 7.41

Source: E. coli

Product Name Recombinant alpha-Synuclein Protein, Human
Molecular Weight The recombinant human SNCA consisting of 140a.a and has a calculated molecular weight of 14.5 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Ala 140
Bioactivity Please contact us for detailed information
Formulation Recombinant alpha-Synuclein Protein was lyophilized from sterile PBS, pH 7.41
Host Species Homo sapiens (Human)
Description The mature form of human SNCA isoform 1 (P37840-1) (Met 1-Ala 140) was expressed and purified
Product Background Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the mitochondria in olfactory bulb, hippocampus, striatum, and thalamus, where the cytosolic alpha-Synuclein was also rich. Normally the unstructured soluble type of alpha-synuclein can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. SNCA abnormality and mitochondrial deficiency are two major changes in the brain of patients with Parkinson's disease (PD). In addition, alpha-synuclein is an abundant component of Lewy bodies in sporadic Parkinson's disease and diffuse Lewy body disease.
Product Memo NACP Protein, Human;PARK1 Protein, Human;PARK4 Protein, Human;PD1 Protein, Human
Product Type Recombinant Protein
Purity Greater than 97% as determined by SDS-PAGE
Source E. coli
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met 1
Uniprot No P37840
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019