Recombinant Aminoacylase 1 Protein, Human (His Tag) Recombinant Proteins The full length of human ACY1 (NP_000657.1) (Met 1-Ser 408) was expressed with a polyhistidine tag at the C-terminus The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Aminoacylase 1 Protein, Human (His Tag)

Formulation: Recombinant Aminoacylase 1 Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol1

Source: Baculovirus-Insect Cells

Product Name Recombinant Aminoacylase 1 Protein, Human (His Tag)
Product Type Recombinant Protein
Source Baculovirus-Insect Cells
Formulation Recombinant Aminoacylase 1 Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol1
Molecular Weight The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 95% as determined by SDS-PAGE
Description The full length of human ACY1 (NP_000657.1) (Met 1-Ser 408) was expressed with a polyhistidine tag at the C-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met 1-Ser 408
Product Background Aminoacylase 1 (ACY1), a metalloenzyme that removes amide-linked ACY1 groups from amino acids and may play a role in regulating responses to oxidative stress. Both the C-terminal fragment found in the two-hybrid screen and full-length ACY1 co-immunoprecipitate with SphK1. Though both C-terminal and full-length proteins slightly reduce SphK1 activity measured in vitro, the C-terminal fragment inhibits while full-length ACY1 potentiates the effects of SphK1 on proliferation and apoptosis. It suggested that ACY1 physically interacts with SphK1 and may influence its physiological functions. As a homodimeric zinc-binding enzyme, Aminoacylase 1 catalyzes the hydrolysis of N alpha-acylated amino acids. Deficiency of Aminoacylase 1 due to mutations in the Aminoacylase 1 (ACY1) gene follows an autosomal-recessive trait of inheritance and is characterized by accumulation of N-acetyl amino acids in the urine.
Memo ACY-1 Protein, Human;ACY1D Protein, Human;HEL-S-5 Protein, Human
Terminal Met
Bioactivity Please contact us for detailed information