Recombinant Aminoacylase 1 Protein, Human (His Tag) Recombinant Proteins The full length of human ACY1 (NP_000657.1) (Met 1-Ser 408) was expressed with a polyhistidine tag at the C-terminus The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Aminoacylase 1 Protein, Human (His Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-204713

Molecular Weight: The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.

Formulation: Recombinant Aminoacylase 1 Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol1

Source: Baculovirus-Insect Cells

Product Name Recombinant Aminoacylase 1 Protein, Human (His Tag)
Molecular Weight The recombinant human ACY1 consists of 419a.a and predicts a molecular weight of 47.3 kDa. It migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
AA Sequence Met 1-Ser 408
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Formulation Recombinant Aminoacylase 1 Protein was lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 10% glycerol1
Host Species Homo sapiens (Human)
Description The full length of human ACY1 (NP_000657.1) (Met 1-Ser 408) was expressed with a polyhistidine tag at the C-terminus
Product Background Aminoacylase 1 (ACY1), a metalloenzyme that removes amide-linked ACY1 groups from amino acids and may play a role in regulating responses to oxidative stress. Both the C-terminal fragment found in the two-hybrid screen and full-length ACY1 co-immunoprecipitate with SphK1. Though both C-terminal and full-length proteins slightly reduce SphK1 activity measured in vitro, the C-terminal fragment inhibits while full-length ACY1 potentiates the effects of SphK1 on proliferation and apoptosis. It suggested that ACY1 physically interacts with SphK1 and may influence its physiological functions. As a homodimeric zinc-binding enzyme, Aminoacylase 1 catalyzes the hydrolysis of N alpha-acylated amino acids. Deficiency of Aminoacylase 1 due to mutations in the Aminoacylase 1 (ACY1) gene follows an autosomal-recessive trait of inheritance and is characterized by accumulation of N-acetyl amino acids in the urine.
Product Memo ACY-1 Protein, Human;ACY1D Protein, Human;HEL-S-5 Protein, Human
Product Type Recombinant Protein
Purity Greater than 95% as determined by SDS-PAGE
Source Baculovirus-Insect Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Met
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019