Recombinant alanyl-tRNA synthetase Protein, Human (His Tag) Recombinant Proteins The human AARS (NP_001596.2) (Met1-Asn968) was expressed with a polyhistidine tag at the N-terminus The recombinant human AARS consists of 987a.a and predicts a molecular weight of 109.2 kDa.
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Formulation: The recombinant human AARS consists of 987a.a and predicts a molecular weight of 109.2 kDa.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant alanyl-tRNA synthetase Protein, Human (His Tag)

Formulation: Recombinant alanyl-tRNA synthetase Protein was lyophilized from sterile 20 mM PB, 500 mM NaCl, pH 7.0, 20 % glycerol.1

Source: Baculovirus-Insect Cells

Product Name Recombinant alanyl-tRNA synthetase Protein, Human (His Tag)
Product Type Recombinant Protein
Source Baculovirus-Insect Cells
Formulation Recombinant alanyl-tRNA synthetase Protein was lyophilized from sterile 20 mM PB, 500 mM NaCl, pH 7.0, 20 % glycerol.1
Molecular Weight The recombinant human AARS consists of 987a.a and predicts a molecular weight of 109.2 kDa.
Endotoxin < 1.0 EU per μg protein as determined by the LAL method
Purity Greater than 85% as determined by SDS-PAGE.
Description The human AARS (NP_001596.2) (Met1-Asn968) was expressed with a polyhistidine tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Met1-Asn968
Product Background Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and aminoacyl-tRNA biosynthesis. Alanyl-tRNA synthetase (AlaRS) catalyzes synthesis of Ala-tRNA (Ala) and hydrolysis of mis-acylated Ser- and Gly-tRNA (Ala) at 2 different catalytic sites. Their role is not confined to catalyze the attachment of amino acids to transfer RNAs and thereby establish the rules of genetic code by virtue of matching the nucleotide triplet of anticodon with cognate amino acid. Under apoptotic conditions in cell culture, the full-length enzyme is secreted, and the two cytokine activities can be generated by leukocyte elastase, an extracellular protease. Secretion of this tRNA synthetase may contribute to apoptosis both by arresting translation and producing needed cytokines. This protein could be an attractive target of drugs against bacterial, fungal and parasitic infections.
Memo CMT2N Protein, Human
Terminal His
Bioactivity Please contact us for detailed information