Recombinant ALDH1A1 Protein, Human (His Tag) Recombinant Proteins The human ALDH1A1 (NP_000680.2) (Ser 2-Ser 501) was expressed, with a polyhistidine tag at the N-terminus The recombinant human ALDH1A1comprises 507a.a and has a predicted molecular weight of 41.5 kDa. It migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
$ $99 In stock
Formulation: The recombinant human ALDH1A1comprises 507a.a and has a predicted molecular weight of 41.5 kDa. It migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
Source: E. coli
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant ALDH1A1 Protein, Human (His Tag)

Formulation: Recombinant ALDH1A1 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 20% glycerol, 1mM DTT, pH 8.01

Source: E. coli

Product Name Recombinant ALDH1A1 Protein, Human (His Tag)
Product Type Recombinant Protein
Source E. coli
Formulation Recombinant ALDH1A1 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 20% glycerol, 1mM DTT, pH 8.01
Molecular Weight The recombinant human ALDH1A1comprises 507a.a and has a predicted molecular weight of 41.5 kDa. It migrates as an approximately 45-50 kDa band in SDS-PAGE under reducing conditions.
Purity Greater than 98% as determined by SDS-PAGE
Description The human ALDH1A1 (NP_000680.2) (Ser 2-Ser 501) was expressed, with a polyhistidine tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Ser 2-Ser 501
Product Background Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. Increased ALDH1A1 activity has been found in the stem cell populations of leukemia and some solid tumors. In tumor specimens, increased ALDH1A1 immunopositivity was found not only in secretory type cancer epithelial cells but also in neuroendocrine tumor populations. ALDH1 has been identified as a reliable marker of breast cancer stem cells. ALDH1 expression in primary cancer is an independent prognostic factor in node-positive breast cancer patients. ALDH1A1 plays a key role in normal hematopoiesis, and as a TLX1 transcriptional target, ALDH1A1 may contribute to the ability of this homeoprotein to alter cell fate and induce tumor growth.
Memo ALDC Protein, Human;ALDH-E1 Protein, Human;ALDH1 Protein, Human;ALDH11 Protein, Human;HEL-9 Protein, Human;HEL-S-53e Protein, Human;HEL12 Protein, Human;PUMB1 Protein, Human;RALDH1 Protein, Human
Terminal Met
Bioactivity Please contact us for detailed information