Recombinant ALDH4A1 Protein, Human (His & GST Tag) Recombinant Proteins The mature form of human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus The recombinant human ALDH4A1/GST chimera consists of 776a.a and has a calculated molecular weight of 86.8 KDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions.
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Formulation: The recombinant human ALDH4A1/GST chimera consists of 776a.a and has a calculated molecular weight of 86.8 KDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant ALDH4A1 Protein, Human (His & GST Tag)

Formulation: Recombinant ALDH4A1 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol1

Source: Baculovirus-Insect Cells

Product Name Recombinant ALDH4A1 Protein, Human (His & GST Tag)
Product Type Recombinant Protein
Source Baculovirus-Insect Cells
Formulation Recombinant ALDH4A1 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol1
Molecular Weight The recombinant human ALDH4A1/GST chimera consists of 776a.a and has a calculated molecular weight of 86.8 KDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 80% as determined by SDS-PAGE
Description The mature form of human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Lys 25-Gln 563
Product Background ALDH4A1 is a member of the aldehyde dehydrogenase family. Aldehyde dehydrogenase enzymes function in the metabolism of many molecules including certain fats (cholesterol and other fatty acids) and protein building blocks (amino acids). Additional aldehyde dehydrogenase enzymes detoxify external substances, such as alcohol and pollutants, and internal substances, such as toxins that are formed within cells. ALDH4A1 is expressed abundantly in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas. It is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation.
Memo ALDH4 Protein, Human;P5CD Protein, Human;P5CDh Protein, Human
Terminal Met
Bioactivity Please contact us for detailed information