Recombinant ALDH4A1 Protein, Human Recombinant Proteins The human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus The secreted recombinant human ALDH4A1 consists of 541a.a and predicts a molecular weight of 59.2 KDa. The apparent molecular weight of the protein is approximately 54 KDa in SDS-PAGE under reducing conditions due to glycosylation.
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Formulation: The secreted recombinant human ALDH4A1 consists of 541a.a and predicts a molecular weight of 59.2 KDa. The apparent molecular weight of the protein is approximately 54 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Source: Baculovirus-Insect Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant ALDH4A1 Protein, Human

Formulation: Recombinant ALDH4A1 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.5.1

Source: Baculovirus-Insect Cells

Product Name Recombinant ALDH4A1 Protein, Human
Product Type Recombinant Protein
Source Baculovirus-Insect Cells
Formulation Recombinant ALDH4A1 Protein was lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.5.1
Molecular Weight The secreted recombinant human ALDH4A1 consists of 541a.a and predicts a molecular weight of 59.2 KDa. The apparent molecular weight of the protein is approximately 54 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Purity Greater than 95% as determined by SDS-PAGE
Description The human ALDH4A1 (AAH07581.1) (Lys 25-Gln 563) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus
Host Species Homo sapiens (Human)
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
AA Sequence Lys 25-Gln 563
Product Background ALDH4A1 is a member of the aldehyde dehydrogenase family. Aldehyde dehydrogenase enzymes function in the metabolism of many molecules including certain fats (cholesterol and other fatty acids) and protein building blocks (amino acids). Additional aldehyde dehydrogenase enzymes detoxify external substances, such as alcohol and pollutants, and internal substances, such as toxins that are formed within cells. ALDH4A1 is expressed abundantly in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas. It is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2). HP-2 is characterized by the accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. The disorder may be causally related to neurologic manifestations, including seizures and mental retardation.
Memo ALDH4 Protein, Human;P5CD Protein, Human;P5CDh Protein, Human
Terminal Gly
Bioactivity Please contact us for detailed information