Recombinant Mouse TIM-3 / HAVCR2 Protein Recombinant Proteins Recombinant mouse TIM-3 / HAVCR2 protein has a calculated molecular mass of 21 kDa. The recombinant protein migrates as 33-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Formulation: Recombinant mouse TIM-3 / HAVCR2 protein has a calculated molecular mass of 21 kDa. The recombinant protein migrates as 33-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Source: HEK293
Usage: Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Mouse TIM-3 / HAVCR2 Protein

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-205608

Molecular Weight: Recombinant mouse TIM-3 / HAVCR2 protein has a calculated molecular mass of 21 kDa. The recombinant protein migrates as 33-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Formulation: Recombinant mouse TIM-3 / HAVCR2 protein was lyophilized from 0.22 μm filtered solution in PBS, pH7.4.

Source: HEK293

Product Name Recombinant Mouse TIM-3 / HAVCR2 Protein
Endotoxin Less than1.0 EU per μg of recombinant mouse TIM-3 / HAVCR2 protein by the LAL method.
Formulation Recombinant mouse TIM-3 / HAVCR2 protein was lyophilized from 0.22 μm filtered solution in PBS, pH7.4.
Host Species Mouse
Molecular Weight Recombinant mouse TIM-3 / HAVCR2 protein has a calculated molecular mass of 21 kDa. The recombinant protein migrates as 33-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Product Background Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428,  KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.
Product Type Recombinant Protein
Purity > 95% as determined by SDS-PAGE.
Source HEK293
Stability Recombinant mouse TIM-3 / HAVCR2 protein was stable up to 12 months from date of receipt at -70℃
Storage Store recombinant mouse TIM-3 / HAVCR2 protein under sterile conditions at -20℃ to -80℃. It is recommended that the recombinant protein be aliquoted for optimal storage.
Synonym HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Terminal Arg 20
Uniprot No Q8VIM0
Usage Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use