Recombinant Mouse MCP1 Protein Recombinant Proteins
$ $99 In stock
Formulation:
Source: E.coli
Usage: Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Mouse MCP1 Protein

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-205918

Formulation: The protein was lyophilized with no additives.

Source: E.coli

Product Name Recombinant Mouse MCP1 Protein
AA Sequence The sequence of the first five N-terminal aas was determined and was found to be Gln-Pro-Asp-Ala-Val.
Bioactivity The biological activity was determined by calculating its ability to chemoattract Balb/C mouse spleen MNCs at 1.0-20.0 ng/ml.
Formulation The protein was lyophilized with no additives.
Host Species Mouse
Product Background Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor ?B (NF?B). CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 aasand a mature peptide of 76 aas. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5.
Product Memo MCP 1 Mouse Monocyte Chemotactic Protein-1 Mouse Recombinant (CCL2)
Product Type Recombinant Protein
Purity > 90% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE
Reconstitution It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions
Source E.coli
Stability Recombinant protein is stable up to 1 year at -80℃
Storage Lyophilized MCP-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Synonym Small inducible cytokine A2, CCL2, Monocyte chemotactic protein 1, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte secretory protein JE, HC11, chemokine (C-C motif) ligand 2, MCP1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434, GDCF-2 HC11, Platelet-derived growth factor-inducible protein JE
Usage Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use