Recombinant Human HDAC5 Protein, His Tag Recombinant Proteins Recombinant Human HDAC5 fused with His tag was expressed in Insect cells
$ $99 In stock
Formulation:
Source: Insect cells
Usage: Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Human HDAC5 Protein, His Tag

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-212412

Formulation: The HDAC5 solution contains 20 mM Tris-HCl buffer (pH 8.0), 300 mM NaCl and 20% Glycerol. Frozen solution

Source: Insect cells

Product Name Recombinant Human HDAC5 Protein, His Tag
Bioactivity > 10000 pmol/min/μg. Assay condition 50 mM Tris-HCl, pH8.0, 136 mM NaCl, 2.8 mM KCl, 1 mM MgCl2, 0.5 mg/ml BSA, 0.005% Tween-20, 20 M AMC-RHKKAc and HDAC5. HDAC reaction was done for 30 min at 37 centigrade followed by treatment with equivoluminal HDAC developer buffer (40 μM Trypsin, 40 μM CaCl2 and 20 μM Trichostatin A for ~60 min at RT.
Endotoxin < 1 EU/μg, determined by LAL method
Formulation The HDAC5 solution contains 20 mM Tris-HCl buffer (pH 8.0), 300 mM NaCl and 20% Glycerol. Frozen solution
Host Species Homo sapiens (human)
Description Recombinant Human HDAC5 fused with His tag was expressed in Insect cells
Product Background HDAC5 is a member of the histone deacetylase family. It is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC5 possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes.
Product Type Recombinant Protein
Purity Greater than 90% by SDS-PAGE analysis.
Source Insect cells
Storage HDAC5 remains stable up to 6 months at -80 centigrade from date of receipt. For maximum recovery of product, centrifuge original vial prior to removing the cap. Aliquot to avoid repeated thawing and freezing.
Synonym HDAC5, histone deacetylase 5, FLJ90614, KIAA0600, NY CO 9, antigen NY-CO-9, HD5, NY-CO-9
Uniprot No Q9UQL6
Usage Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019