Recombinant Human HDAC3 (Active) Protein, GST Tag Recombinant Proteins Full-length recombinant human HDAC3 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag
$ $99 In stock
Formulation:
Source: Sf9 Cells
Usage: Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Human HDAC3 (Active) Protein, GST Tag

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-212428

Formulation: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol

Source: Sf9 Cells

Product Name Recombinant Human HDAC3 (Active) Protein, GST Tag
Bioactivity 125RLU/min/ng
Formulation Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
Host Species Homo sapiens (human)
Description Full-length recombinant human HDAC3 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag
Product Background HDAC3 or Histone deacetylase 3 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex that represses transcription when tethered to a promoter. HDAC3 may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. HDAC3 can also down-regulate p53 function and thus modulate cell growth and apoptosis. Catalytic domain of HDAC4 can interact with HDAC3 via the transcriptional corepressor NCOR2. RELA is a nonhistone substrate of HDAC3 and IKBA-dependent nuclear export of the HDAC3-deacetylated RELA replenishes the depleted cytoplasmic pool of latent NFKB-IKBA complexes.
Product Type Recombinant Protein
Purity Greater than 70%
Source Sf9 Cells
Storage Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Synonym HDAC3, histone deacetylase 3, HD3, RPD3, RPD3 2, SMAP45, RPD3-2
Uniprot No O15379
Usage Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use
Last Modified Mar 08 2019