Recombinant SIRP gamma Protein, Human (Fc Tag) Recombinant Proteins The human SIRPG (NP_061026.2) (Met1-Ser364) was expressed with the Fc region of human IgG1 at the C-terminus The recombinant human SIRPG consists of 577a.a and predicts a molecular weight of 64.1 kDa.
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Formulation: The recombinant human SIRPG consists of 577a.a and predicts a molecular weight of 64.1 kDa.
Source: HEK293 Cells
Usage: Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant SIRP gamma Protein, Human (Fc Tag)

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-214205

Molecular Weight: The recombinant human SIRPG consists of 577a.a and predicts a molecular weight of 64.1 kDa.

Formulation: Recombinant SIRP gamma Protein was lyophilized from sterile PBS, pH 7.4.1

Source: HEK293 Cells

Product Name Recombinant SIRP gamma Protein, Human (Fc Tag)
Molecular Weight The recombinant human SIRPG consists of 577a.a and predicts a molecular weight of 64.1 kDa.
AA Sequence Met1-Ser364
Bioactivity Please contact us for detailed information
Endotoxin < 1.0 EU per μg protein as determined by the LAL method
Formulation Recombinant SIRP gamma Protein was lyophilized from sterile PBS, pH 7.4.1
Host Species Homo sapiens (Human)
Description The human SIRPG (NP_061026.2) (Met1-Ser364) was expressed with the Fc region of human IgG1 at the C-terminus
Product Background Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPG/SIRP gamma/CD172g is probable immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG can mediate cell-cell adhesion. SIRPG/SIRP gamma is engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG/SIRP gamma/CD172g is detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD2+ cells, and all activated NK cells. This cytokine is mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, SIRPG is primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection.
Product Memo bA77C3.1 Protein, Human;CD172g Protein, Human;SIRP-B2 Protein, Human;SIRPB2 Protein, Human;SIRPgamma Protein, Human
Product Type Recombinant Protein
Purity Greater than 90% as determined by SDS-PAGE.
Source HEK293 Cells
Storage Store recombinant protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Terminal Glu 29
Usage Our products are for research use only. This product is not intended or approved for human, diagnostics or veterinary use