Recombinant Human ABL1 Protein, GST-His Tag Recombinant Proteins Human ABL1 (NM_005157.3, 118 a.a. - 535 a.a.) partial recombinant protein with GST-His tag was expressed in Sf9 cells
$ $99 In stock
Formulation:
Source: Insect cell
Usage: Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use

Recombinant Human ABL1 Protein, GST-His Tag

The product is for non-human research only. Not for therapeutic or veterinary use.

Catalog No: bt-217802

Formulation: Liquid

Source: Insect cell

Product Name Recombinant Human ABL1 Protein, GST-His Tag
Bioactivity 75 pmol/ug x min
Description Human ABL1 (NM_005157.3, 118 a.a. - 535 a.a.) partial recombinant protein with GST-His tag was expressed in Sf9 cells
Formulation Liquid
Host Species Homo sapiens (human)
Product Background This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [provided by RefSeq, Aug 2014]
Product Type Recombinant Protein
Source Insect cell
Storage Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing
Synonym ABL1, c-abl oncogene 1, non-receptor tyrosine kinase, ABL, c abl oncogene 1, receptor tyrosine kinase , v abl Abelson murine leukemia viral oncogene homolog 1, tyrosine-protein kinase ABL1, c ABL, JTK7, p150, proto-oncogene c-Abl, bcr/c-abl oncogene protein, Abelson tyrosine-protein kinase 1, c-abl oncogene 1, receptor tyrosine kinase, proto-oncogene tyrosine-protein kinase ABL1, v-abl Abelson murine leukemia viral oncogene homolog 1, ABL, c-ABL, v-abl, bcr/abl
Uniprot No P00519
Usage Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use