Recombinant Human LAIR2 Protein
The product is for non-human research only. Not for therapeutic or veterinary use.
Catalog No: bt-221455
Formulation: LAIR2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
|Product Name||Recombinant Human LAIR2 Protein|
|AA Sequence||MGSSHHHHHH SSGLVPRGSH MGSHMQEGAL PRPSISAEPG TVISPGSHVT FMCRGPVGVQ TFRLEREDRA KYKDSYNVFR LGPSESEARF HIDSVSEGNA GLYRCLYYKP PGWSEHSDFL ELLVKGTVPG TEASGFDAP.|
|Formulation||LAIR2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.|
|Host Species||Homo sapiens (Human)|
|Product Background||Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) is a secreted, 131aa protein which contains one IglikeC2 type domain, rendering it a member of the Ig superfamily. Even though one is secreted and one is membrane bound, the 2 LAIR proteins are assumed to have evolved from a common gene ancestor and seem to share similar adhesion profiles, suggesting that LAIR2 may compete with LAIR1 for ligand binding. LAIR2 was discovered by its similarity to LAIR1, which is an inhibitory receptor present on mononuclear leukocytes. The LAIR2 gene maps to a region of 19q13.4, dubbed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily, including LAIR1. The function of the LAIR2 protein is unknown, though it is assumed to be secreted and may help modulate mucosal tolerance.|
|Product Memo||LAIR2 Human Leukocyte-Associated Ig-Like Receptor 2 Human Recombinant|
|Product Type||Recombinant Protein|
|Purity||>90% as determined by SDS-PAGE.|
|Stability||Recombinant protein is stable up to 1 year at -80℃|
|Storage||Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid repeated freeze-thaw cycles.|
|Synonym||Leukocyte-associated immunoglobulin-like receptor 2, LAIR-2, CD306, LAIR2|
|Usage||Our recombinant proteins are For Research Use Only. This product is not intended or approved for human, diagnostics or veterinary use|