pros-1 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
14-16 weeks (made-to-order)
Synonyms
pros-1 antibody; ceh-26 antibody; K12H4.1 antibody; Homeobox protein prospero homolog 1 antibody; Homeobox protein ceh-26 antibody
Target Names
pros-1
Uniprot No.

Target Background

Function
PROS-1 is a transcription factor implicated in developmental processes, specifically regulating the transcription of genes essential for excretory canal formation.
Gene References Into Functions

Further research indicates PROS-1's crucial role in development. Studies using C. elegans have demonstrated that pros-1 deletion results in larval lethality, a phenotype rescued by both pros-1 and human Prox1 transgenes. Moreover, RNAi-mediated knockdown of pros-1 impacted sensory neuron function, affecting morphology, sensory behavior, and cold tolerance. These findings collectively highlight PROS-1's function as a transcriptional regulator in glial cells. (PMID: 27402188)

Database Links

KEGG: cel:CELE_K12H4.1

STRING: 6239.K12H4.1

UniGene: Cel.10675

Protein Families
Prospero homeodomain family
Subcellular Location
Nucleus.

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