PUB23 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PUB23 antibody; At2g35930 antibody; F11F19.16 antibody; E3 ubiquitin-protein ligase PUB23 antibody; EC 2.3.2.27 antibody; Plant U-box protein 23 antibody; RING-type E3 ubiquitin transferase PUB23 antibody; U-box domain-containing protein 23 antibody
Target Names
PUB23
Uniprot No.

Target Background

Function

PUB23 is an E3 ubiquitin-protein ligase that negatively regulates the plant's response to water stress. In coordination with PUB22, it may control a drought signaling pathway through the ubiquitination of cytosolic RPN12a. Furthermore, PUB23 acts as a negative regulator of pathogen-associated molecular pattern (PAMP)-triggered immunity, functioning in conjunction with PUB22 and PUB24.

Gene References Into Functions
  • RPN6 exhibits a shorter protein half-life in PUB22-overexpressing plants compared to wild-type plants. Conversely, RPN6 is significantly stabilized in pub22 pub23 double knockout plants. PMID: 26188517
  • Research indicates that PUB23 and its partners coordinately regulate a drought signaling pathway via the ubiquitination of cytosolic RPN12a in Arabidopsis thaliana. PMID: 18664614
  • A study demonstrates the negative regulation of PAMP-triggered immunity by the E3 ubiquitin ligase complex comprising PUB22, PUB23, and PUB24 in Arabidopsis thaliana. PMID: 18771922
Database Links

KEGG: ath:AT2G35930

STRING: 3702.AT2G35930.1

UniGene: At.43241

Subcellular Location
Cytoplasm.

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