PYL2 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
PYL2 antibody; RCAR14 antibody; At2g26040 antibody; T19L18.15 antibody; Abscisic acid receptor PYL2 antibody; PYR1-like protein 2 antibody; Regulatory components of ABA receptor 14 antibody
Target Names
PYL2
Uniprot No.
Target Background
Function
PYL2 is a receptor for abscisic acid (ABA), playing a crucial role in ABA-mediated responses such as stomatal closure and germination inhibition. Upon activation by ABA, PYL2 inhibits the activity of group-A protein phosphatases type 2C (PP2Cs). Notably, both (-)-ABA and (+)-ABA can activate PYL2.
Gene References Into Functions
- Research indicates that the subfamily III of ABA receptors, including PYL2, plays a pivotal role in ABA-mediated developmental processes and, more importantly, contributes to drought tolerance through the ABA-dependent pathway. PMID: 30004422
- Deletion of the PYL2 gene alters the phosphorylation pattern of SnRK2 in response to abscisic acid signaling. PMID: 25693798
- A study has unveiled the structure of a SnRK2-PP2C complex, revealing a remarkable similarity in PP2C recognition by SnRK2 and ABA receptors. This structural data provides a straightforward mechanism directly linking ABA binding to SnRK2 kinase activation. PMID: 22116026
- Subtle variations in the binding pockets of PYR/PYL proteins, including PYL2, control ligand orientation within the pocket. This variation explains the effectiveness of pyrabactin as a receptor agonist. PMID: 20729860
Database Links
KEGG: ath:AT2G26040
STRING: 3702.AT2G26040.1
Protein Families
PYR/PYL/RCAR abscisic acid intracellular receptor family
Subcellular Location
Cytoplasm. Nucleus. Cell membrane.
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