tgt-2 Antibody

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Product Specs

Buffer
Preservative: 0.03% ProClin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4.
Form
Liquid
Lead Time
14-16 week lead time (made-to-order)
Synonyms
tgt-2 antibody; Y39B6A.35Queuine tRNA-ribosyltransferase accessory subunit 2 antibody; Queuine tRNA-ribosyltransferase domain-containing protein 1 antibody
Target Names
tgt-2
Uniprot No.

Target Background

Function
The non-catalytic subunit of queuine tRNA-ribosyltransferase (TGT). This enzyme catalyzes the base exchange of guanine (G) with queuine (Q) at the 34th position (wobble position within the anticodon) of tRNAs containing GU(N) anticodons (specifically tRNA-Asp, -Asn, -His, and -Tyr). This process results in the formation of the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
Database Links

KEGG: cel:CELE_Y39B6A.35

STRING: 6239.Y39B6A.35

UniGene: Cel.1830

Protein Families
Queuine tRNA-ribosyltransferase family, QTRT2 subfamily
Subcellular Location
Cytoplasm.

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