rnf213b Antibody
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In Stock 
Description
Product Overview
The RNF213 antibody is available in multiple formats, each optimized for specific research applications:
Key Features:
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Specificity: Targets the N-terminal domain of RNF213 (e.g., clone 1C9 in EMD Millipore’s antibody).
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Reactivity: Validated in human samples, including HUVEC cells (Proteintech) and A549 cells (Abcam).
Research Applications
RNF213 antibodies have been instrumental in elucidating the protein’s roles in:
Mechanistic Insights:
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Lipid Metabolism: RNF213 inhibits lipolysis and regulates fatty acid desaturation (UniProtKB/Swiss-Prot, ).
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Immune Signaling: Mediates ubiquitination of viral proteins (e.g., KSHV’s RTA) and bacterial components (e.g., Salmonella LPS) .
Clinical Implications
RNF213 antibodies are pivotal in studying diseases linked to RNF213:
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Composition: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Composition: 50% Glycerol, 0.01M Phosphate Buffered Saline (PBS), pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
rnf213b antibody; E3 ubiquitin-protein ligase rnf213-beta antibody; EC 2.3.2.27 antibody; EC 3.6.4.- antibody; Mysterin-B antibody; Mysterin-beta antibody; RING finger protein 213-B antibody; RING finger protein 213-beta antibody; RING-type E3 ubiquitin transferase rnf213-beta antibody
Target Names
rnf213b
Uniprot No.
Target Background
Function
Exhibits both E3 ubiquitin-protein ligase and ATPase enzymatic activities.
Database Links
STRING: 7955.ENSDARP00000110447
Protein Families
AAA ATPase family
Subcellular Location
Cytoplasm, cytosol.
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