RDL4 Antibody

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Description

Introduction to RDL4 Antibody

RDL4 Antibody is a research tool targeting a protein encoded by the AT4G11310 gene in Arabidopsis thaliana. This protein belongs to the peptidase C1 family and is annotated as a probable cysteine protease (EC 3.4.22.-). While limited experimental data exist, the antibody is primarily used in plant molecular biology to study protease activity, cellular localization, and functional roles in development or stress responses.

Target Protein Characteristics

The RDL4 protein is part of the RD21A-like protease family, implicated in plant stress responses. Key features include:

PropertyDetail
Gene IDAT4G11310
Protein FamilyPeptidase C1 (cathepsin-like cysteine proteases)
ExpressionDetected in inflorescences
FunctionLikely involved in proteolytic processes, though precise roles are uncharacterized
OrthologsRD21A-like proteases in Arabidopsis and related species

Potential Research Applications

While no peer-reviewed studies explicitly report RDL4 Antibody usage, its design aligns with applications in:

  • Protease Activity Studies: Investigating cysteine protease roles in plant stress adaptation or developmental processes.

  • Subcellular Localization: Tracking RDL4 protein distribution in tissues (e.g., inflorescences).

  • Functional Validation: Pairing with CRISPR-Cas9 gene editing to confirm antibody specificity .

Comparison with Insect RDL Antibodies

A separate line of research focuses on RDL (Resistance to Dieldrin), a GABA receptor subunit in insects (e.g., Drosophila, Apis mellifera). Antibodies against RDL are used to study neurotoxicity and pest resistance mechanisms . Key distinctions:

FeaturePlant RDL4 AntibodyInsect RDL Antibody
TargetCysteine protease (plant)GABA receptor subunit (insect)
FunctionProteolytic activityIon channel regulation
ApplicationsPlant molecular biologyNeurotoxicity, pesticide resistance studies
ValidationPeptide preadsorptionCRISPR-Cas9 knockout models

Research Gaps and Future Directions

  • Limited Functional Data: No studies directly link RDL4 to specific biological processes.

  • Cross-Species Relevance: Antibody utility in non-Arabidopsis species remains untested.

  • Technological Integration: Combining RDL4 Antibody with single-cell proteomics or CRISPR screens could elucidate its role in plant biology.

Product Specs

Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
RDL4 antibody; CP1 antibody; At4g11310 antibody; F8L21.100 antibody; Probable cysteine protease RDL4 antibody; EC 3.4.22.- antibody; Cysteine protease 1 antibody; AtCP1 antibody; Probable cysteine proteinase At4g11310 antibody; RD21A-like protease 4 antibody
Target Names
RDL4
Uniprot No.

Target Background

Function
This antibody targets a protein that is likely a thiol protease.
Database Links

KEGG: ath:AT4G11310

STRING: 3702.AT4G11310.1

UniGene: At.43189

Protein Families
Peptidase C1 family
Tissue Specificity
Expressed in inflorescences.

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