Recombinant Arabidopsis thaliana ABC transporter G family member 17 (ABCG17)
Description
Functional Role in ABA Homeostasis
ABCG17, alongside its homolog ABCG18, regulates ABA distribution and metabolism under non-stress conditions :
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ABA Import: Localized to plasma membranes of shoot mesophyll and stem cortex cells, ABCG17 facilitates ABA uptake into parenchyma cells, promoting conjugation to inactive ABA-glucosyl ester (ABA-GE) .
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Stomatal Regulation: By sequestering ABA into storage forms, ABCG17 limits free ABA availability in guard cells, thereby reducing stomatal closure and transpiration .
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Long-Distance Translocation: ABCG17 modulates ABA movement from shoots to roots, influencing lateral root development .
Gene Expression and Localization
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Tissue Specificity: ABCG17 is primarily expressed in shoot mesophyll and stem cortex cells, with no detectable activity in vascular tissues .
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Stress Response: Under abiotic stress (e.g., drought), ABCG17 transcription is suppressed, enhancing free ABA availability for stress responses .
Research Findings from Mutant Studies
Key insights from genetic studies include:
Table 1: Phenotypic Effects of ABCG17 Manipulation
Recombinant Production and Applications
The recombinant ABCG17 protein is critical for:
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In vitro studies: Investigating ABA transport mechanisms and kinetics .
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Structural analysis: Mapping ATP-binding and substrate-interaction domains .
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Agricultural biotechnology: Engineering crops with optimized ABA responses for drought resistance .
Future Directions
Current research gaps include:
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Elucidating ABCG17’s role in ABA-GE subcellular trafficking.
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Developing inhibitors/activators for precision agriculture.
Product Specs
Note: We will prioritize shipping the format currently in stock. However, if you require a specific format, please indicate your preference when placing your order, and we will accommodate your request.
Note: All of our proteins are shipped with standard blue ice packs. If you require dry ice shipping, please inform us in advance, and additional fees will apply.
Generally, the shelf life of the liquid form is 6 months at -20°C/-80°C. The shelf life of the lyophilized form is 12 months at -20°C/-80°C.
