Recombinant Arabidopsis thaliana Secretory carrier-associated membrane protein 3 (SCAMP3)
Description
Functional Roles in Arabidopsis thaliana
SCAMP3 facilitates post-Golgi trafficking and endosomal sorting, impacting:
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Vesicle Transport: Mediates secretory vesicle clustering and cargo delivery to the plasma membrane ( ).
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Cell Wall Synthesis: Supports xylem development by transporting extracellular polysaccharides and cell wall precursors ( ).
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Stress Response: Modulates membrane recycling under abiotic stress, though direct evidence in Arabidopsis requires further study ( ).
Evolutionary and Comparative Analysis
SCAMP3 is evolutionarily conserved across plants. A comparative study of SCAMP genes in A. thaliana, Populus trichocarpa, and Manihot esculenta revealed:
| Species | SCAMP Homologs | Functional Overlap |
|---|---|---|
| A. thaliana | SCAMP1-5 | Membrane trafficking, stress response |
| Hevea brasiliensis | HbSCAMP3 | Xylem development, growth regulation |
| Oryza sativa | OsSCAMP3 | Vesicle-mediated transport |
SCAMP3 homologs in woody plants (e.g., rubber tree) show stronger evolutionary ties to A. thaliana than herbaceous species ( ).
Subcellular Localization
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SCAMP3 localizes to the plasma membrane and secretory vesicles in tobacco epidermal cells, suggesting conserved trafficking roles ( ).
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Interacts with ER–Golgi–TGN–PM pathways, dependent on N-terminal domains ( ).
Functional Knockdown Studies
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Reduced SCAMP3 expression in Arabidopsis mutants correlates with impaired vesicle clustering and slowed growth ( ).
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Regulatory Pathways: Associates with oxidative phosphorylation and chromatin remodeling networks ( ).
Applications in Plant Biology
Future Directions
Product Specs
Note: We prioritize shipping the format currently in stock. However, if you have specific format requirements, please indicate them during order placement. We will fulfill your request if possible.
Note: Our proteins are shipped with standard blue ice packs. If dry ice shipping is required, please inform us in advance. Additional fees will apply.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
