Recombinant Candida glabrata 40S ribosomal protein S22 (RPS22)
Description
Introduction to Recombinant Candida glabrata 40S Ribosomal Protein S22 (RPS22)
Recombinant Candida glabrata 40S ribosomal protein S22 (RPS22) is a protein produced through recombinant DNA technology. This protein is part of the 40S subunit of the ribosome in Candida glabrata, a species of yeast known for its pathogenicity and resistance to antifungal drugs . The recombinant form of RPS22 is used in research to study various aspects of ribosomal function, protein synthesis, and potentially in the development of diagnostic tools or therapeutic agents.
Structure and Function of RPS22
RPS22 is a component of the small subunit of the ribosome, which plays a crucial role in protein synthesis by decoding messenger RNA (mRNA) sequences into specific amino acid chains. The protein sequence of RPS22 from Candida glabrata is well-defined, with a specific amino acid sequence that contributes to its structural and functional properties .
| Property | Description |
|---|---|
| Sequence | TRSSVLADA LNAINNAEKT GKRQVLIRPS SKVIIKFLQV MQRHGYIGEF EYIDDHRSGK IVVQLNGRLN KCGVISPRFN VKIGDIEKWT ANLLPARQFG YVILTTSAGI MDHEEARRKH VSGKILGFVY |
| Uniprot No. | Q6FMW9 |
| Purity | >85% (SDS-PAGE) |
| Immunogen Species | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) |
Potential Applications
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Diagnostic Tools: Recombinant RPS22 could be used to develop diagnostic assays for detecting Candida glabrata infections, especially in cases where traditional methods are less effective.
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Therapeutic Targets: Studying the function of RPS22 and other ribosomal proteins might reveal vulnerabilities in the protein synthesis machinery of Candida glabrata, potentially leading to new antifungal strategies.
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Basic Research: The recombinant protein can serve as a tool for investigating ribosome structure and function, contributing to broader knowledge of protein synthesis mechanisms.
Product Specs
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