Cauri_0028 is commercially available in two recombinant forms:
Full-Length Protein (E. coli Origin):
Partial Protein (Baculovirus Origin):
Though cauri_0028 has not been directly studied in pathogenicity, its role as a membrane protein positions it as a candidate for:
Vaccine Development: Membrane proteins are often targets for immunological research .
Biochemical Assays: Used to study membrane dynamics or protein-protein interactions in Corynebacterium spp. .
Clinical Context:
While C. aurimucosum is rarely pathogenic, cases of bacteremia and urinary tract infections have been reported, highlighting the need for deeper understanding of its membrane components . For example, a 94-year-old patient with C. aurimucosum bacteremia was treated successfully with amoxicillin/clavulanic acid, underscoring the bacterium’s clinical relevance .
| Feature | C. aurimucosum | Pathogenic Corynebacteria |
|---|---|---|
| Core Genome Genes | 1,048 (shared) | 1,048 (shared) |
| Prophage Regions | ϕCauriI (20.7 kb), ϕCauriII (51.5 kb) | Variable |
| CRISPR Systems | Present | Present (e.g., C. jeikeium) |
KEGG: car:cauri_0028
STRING: 548476.CaurA7_010100003951