Recombinant Danio rerio Rab11 family-interacting protein 3 (rab11fip3), partial

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Cat. No.

BT2475032

Source

Yeast

Synonyms

rab11fip3; si:ch211-153c20.4; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT2475032

Source

E.coli

Synonyms

rab11fip3; si:ch211-153c20.4; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT2475032

Source

E.coli

Synonyms

rab11fip3; si:ch211-153c20.4; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT2475032

Source

Baculovirus

Synonyms

rab11fip3; si:ch211-153c20.4; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT2475032

Source

Mammalian cell

Synonyms

rab11fip3; si:ch211-153c20.4; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3

Purity

>85% (SDS-PAGE)

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Description

Overview

Recombinant Danio rerio Rab11 family-interacting protein 3 (rab11fip3), partial, refers to a synthetically produced fragment of the Rab11 family-interacting protein 3 (rab11fip3) derived from the zebrafish (Danio rerio) . Rab11fip3 is a protein that interacts with Rab GTPases, which are involved in regulating intracellular vesicle trafficking .

Function and Significance

Rab11fip3 is involved in the movement of peripheral sorting endosomes along microtubule tracks towards the microtubule organizing center . As a Rab11 effector protein, Rab11fip3 recognizes the GTP-bound form of RAB11 . The functional Rab11-RAB11FIP3 complex regulates the movement of peripheral sorting endosomes (SE) along microtubule tracks toward the microtubule organizing center .

Interactions

Rab11-family interacting proteins (Rab11-FIPs) interact with and regulate Rab GTPases .

Impact of Chemical compounds on Rab11fip3 Expression

Chemical Compound	Effect on Rab11fip3 Expression	Species
2,3,7,8-tetrachlorodibenzodioxine	Decreases expression	Rat
2-methylcholine	Affects expression	Rat
2-palmitoylglycerol	Increases expression	Rat
3,4-methylenedioxymethamphetamine	Increases expression	Rat
Cisplatin	Decreases expression	Rat
Copper(II) sulfate	Decreases expression	Rat
Cyclosporin A	Decreases methylation	Rat
Dibutyl phosphate	Affects expression	Rat
Diclofenac	Increases expression	Rat
Dorsomorphin	Decreases expression	Rat
Ethanol	Affects expression and splicing	Rat
Folic acid	Decreases expression	Rat
Fulvestrant	Increases methylation	Rat
L-methionine	Decreases expression	Rat
Leflunomide	Increases expression	Rat
Levonorgestrel	Decreases expression	Rat
Malathion	Increases expression	Rat
Mercury dichloride	Decreases expression	Rat
Methyl methanesulfonate	Increases expression	Rat
Methylmercury chloride	Increases expression	Rat
Paracetamol	Affects expression	Rat
Perfluorononanoic acid	Decreases expression	Rat
Perfluorooctane-1-sulfonic acid	Multiple interactions	Rat

Product Specs

Form

Lyophilized powder
Note: While we prioritize shipping the format currently in stock, please specify your format preference in order notes for customized preparation.

Lead Time

Delivery times vary depending on the purchase method and location. Please contact your local distributor for precise delivery estimates.
Note: Standard shipping includes blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.

Notes

Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.

Reconstitution

Centrifuge the vial briefly before opening to settle the contents. Reconstitute the protein in sterile, deionized water to a concentration of 0.1-1.0 mg/mL. We recommend adding 5-50% glycerol (final concentration) and aliquoting for long-term storage at -20°C/-80°C. Our default glycerol concentration is 50% and can serve as a guideline.

Shelf Life

Shelf life depends on storage conditions, buffer composition, temperature, and protein stability. Generally, liquid formulations have a 6-month shelf life at -20°C/-80°C, while lyophilized formulations have a 12-month shelf life at -20°C/-80°C.

Storage Condition

Store at -20°C/-80°C upon receipt. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.

Tag Info

The tag type is determined during the manufacturing process.
If you require a specific tag type, please inform us, and we will prioritize its development.

Synonyms

rab11fip3; si:ch211-153c20.4; Rab11 family-interacting protein 3; FIP3-Rab11; Rab11-FIP3

Buffer Before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Datasheet

Please contact us to get it.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Species

Danio rerio (Zebrafish) (Brachydanio rerio)

Target Names

rab11fip3

Uniprot No.

Q7T005

Target Background

Function

This protein regulates endocytic trafficking by mediating membrane delivery. It's essential for cytokinesis abscission, potentially acting as an 'address tag' directing recycling endosome membranes to the cleavage furrow during late cytokinesis. It also maintains the structural integrity of the endosomal recycling compartment during interphase. It may function as an adapter protein linking the dynein motor complex to various cargos.

Database Links

STRING: 7955.ENSDARP00000013205

UniGene: Dr.135100

Subcellular Location

Recycling endosome membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody.

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Recombinant Danio rerio Rab11 family-interacting protein 3 (rab11fip3), partial

Description

Overview

Function and Significance

Interactions

Impact of Chemical compounds on Rab11fip3 Expression

Product Specs

Target Background

Quick Inquiry

Category

Service