Dictyostelium discoideum is a powerful tool for studying cellular and developmental biology. It has a relatively small genome of about 34 Mb, which facilitates targeted gene disruption and the study of specific gene functions . This organism is used extensively in research on cell signaling, chemotaxis, and developmental processes .
Recombinant proteins produced in Dictyostelium can have various applications, including drug discovery and the study of disease mechanisms. For example, compounds like DIF-1, which induce stalk-cell differentiation, have been explored for their potential in drug development . Additionally, Dictyostelium has been used to model human diseases such as mucolipidosis type IV, highlighting its versatility in biomedical research .
While specific data on Recombinant Dictyostelium discoideum Colossin-C (colC), partial is not available, research on Dictyostelium often involves studying gene functions and protein activities through genetic manipulation. For instance, the use of Cre-loxP systems allows for efficient gene disruption and recycling of selectable markers, enabling complex genetic studies .
KEGG: ddi:DDB_G0281507
STRING: 44689.DDB0237870