Recombinant Dictyostelium discoideum Colossin-C (colC), partial

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Description

Overview of Dictyostelium discoideum as a Model Organism

Dictyostelium discoideum is a powerful tool for studying cellular and developmental biology. It has a relatively small genome of about 34 Mb, which facilitates targeted gene disruption and the study of specific gene functions . This organism is used extensively in research on cell signaling, chemotaxis, and developmental processes .

Potential Applications of Recombinant Proteins in Dictyostelium

Recombinant proteins produced in Dictyostelium can have various applications, including drug discovery and the study of disease mechanisms. For example, compounds like DIF-1, which induce stalk-cell differentiation, have been explored for their potential in drug development . Additionally, Dictyostelium has been used to model human diseases such as mucolipidosis type IV, highlighting its versatility in biomedical research .

Research Findings and Data

While specific data on Recombinant Dictyostelium discoideum Colossin-C (colC), partial is not available, research on Dictyostelium often involves studying gene functions and protein activities through genetic manipulation. For instance, the use of Cre-loxP systems allows for efficient gene disruption and recycling of selectable markers, enabling complex genetic studies .

Example Table: Applications of Dictyostelium in Biomedical Research

ApplicationDescriptionRelevance
Drug DiscoveryDictyostelium is a source of novel compounds like DIF-1 for drug development.Potential therapeutic agents .
Disease ModelingUsed to study diseases such as mucolipidosis type IV and neurodegenerative disorders.Understanding disease mechanisms .
Cellular BiologyStudies on chemotaxis, cell signaling, and developmental processes.Insights into basic biological processes .

Product Specs

Form
Lyophilized powder.
Note: While we will prioritize shipping the format currently in stock, please specify your format preference in order notes for customized fulfillment.
Lead Time
Delivery times vary depending on the purchasing method and location. Please contact your local distributor for precise delivery estimates.
Note: All protein shipments include standard blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.
Notes
Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.
Reconstitution
Centrifuge the vial briefly before opening to collect the contents. Reconstitute the protein in sterile, deionized water to a concentration of 0.1-1.0 mg/mL. For long-term storage, we recommend adding 5-50% glycerol (final concentration) and aliquoting at -20°C/-80°C. Our standard glycerol concentration is 50% and can serve as a reference.
Shelf Life
Shelf life depends on various factors including storage conditions, buffer composition, temperature, and protein stability. Generally, liquid formulations have a 6-month shelf life at -20°C/-80°C, while lyophilized forms have a 12-month shelf life at -20°C/-80°C.
Storage Condition
Upon receipt, store at -20°C/-80°C. Aliquoting is essential for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
Tag type is determined during the manufacturing process.
The tag type is determined during production. If a specific tag type is required, please inform us, and we will prioritize its development.
Synonyms
colC; DDB_G0281507Colossin-C
Buffer Before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Datasheet
Please contact us to get it.
Protein Length
Partial
Purity
>85% (SDS-PAGE)
Species
Dictyostelium discoideum (Slime mold)
Target Names
colC
Uniprot No.

Target Background

Database Links
Protein Families
Serine-aspartate repeat-containing protein (SDr) family
Subcellular Location
Secreted.

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