Recombinant Elliptorhina sp. Sulfakinin-1

Shipped with Ice Packs

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Cat. No.

BT47536

Source

Yeast

Synonyms

; Sulfakinin-1; EllSp-SK-1

Purity

>85% (SDS-PAGE)

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Cat. No.

BT47536

Source

E.coli

Synonyms

; Sulfakinin-1; EllSp-SK-1

Purity

>85% (SDS-PAGE)

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Cat. No.

BT47536

Source

E.coli

Synonyms

; Sulfakinin-1; EllSp-SK-1

Purity

>85% (SDS-PAGE)

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Cat. No.

BT47536

Source

Baculovirus

Synonyms

; Sulfakinin-1; EllSp-SK-1

Purity

>85% (SDS-PAGE)

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Cat. No.

BT47536

Source

Mammalian cell

Synonyms

; Sulfakinin-1; EllSp-SK-1

Purity

>85% (SDS-PAGE)

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Description

Introduction to Recombinant Elliptorhina sp. Sulfakinin-1

Recombinant Elliptorhina sp. Sulfakinin-1 is a synthetic form of the neuropeptide Sulfakinin-1 derived from the Hisser roach (Elliptorhina sp. strain SR-2005). Sulfakinins are evolutionarily conserved neuropeptides that regulate feeding behavior, digestion, and energy homeostasis in insects and other arthropods . This recombinant variant is engineered for research applications, enabling studies on sulfakinin signaling pathways and their physiological roles.

Notes:

Tagging: Tag type (e.g., His-tag) is determined during manufacturing .
Buffers: Tris/PBS-based with 6% trehalose for stability .

Table 2: Functional Roles of Sulfakinins in Insects

Species	Function	Mechanism
Bactrocera dorsalis	Promotes foraging, suppresses mating	Modulates odorant receptor expression
Dendroctonus armandi	Reduces feeding, regulates energy balance	Increases trehalose, decreases glycogen
Bombyx mori	Inhibits food intake	Activates BNGR-A9 receptor signaling

Key Mechanisms:

Receptor Binding: Sulfakinins activate G protein-coupled receptors (e.g., SkR1), altering intracellular Ca²⁺ and ERK1/2 signaling .
Behavioral Modulation: In B. dorsalis, sulfakinin enhances sensitivity to food odors while suppressing pheromone detection .

Applications in Research

Feeding Behavior Studies: Used to investigate appetite regulation and satiety mechanisms in insects .
Receptor-Ligand Assays: Validates interactions with sulfakinin receptors (e.g., SkR1, BNGR-A9) .
Comparative Evolutionary Studies: Explores conserved signaling pathways across bilaterians .

Limitations and Future Directions

Species-Specificity: Functional differences between sulfakinin analogs (e.g., Elliptorhina vs. Drosophila) require further characterization.
Sulfation Status: Bioactivity may depend on tyrosine sulfation, necessitating peptide modification studies .

Product Specs

Form

Lyophilized powder. We will ship the available format, but you can request a specific format when ordering.

Lead Time

Delivery times vary. Contact your local distributor for details. Proteins are shipped with blue ice packs. Request dry ice in advance (extra fees apply).

Notes

Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.

Reconstitution

Briefly centrifuge the vial before opening. Reconstitute in sterile deionized water to 0.1-1.0 mg/mL. Add 5-50% glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final glycerol concentration is 50%.

Shelf Life

Shelf life depends on storage conditions, buffer, temperature, and protein stability. Liquid form: 6 months at -20°C/-80°C. Lyophilized form: 12 months at -20°C/-80°C.

Storage Condition

Store at -20°C/-80°C upon arrival. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.

Tag Info

Tag type is determined during manufacturing. If you require a specific tag, please inform us, and we will prioritize its development.

Synonyms

; Sulfakinin-1; EllSp-SK-1

Buffer Before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Datasheet

Please contact us to get it.

Expression Region

1-11

Protein Length

Cytoplasmic domain

Purity

>85% (SDS-PAGE)

Species

Elliptorhina sp. (strain SR-2005) (Hisser roach)

Target Protein Sequence

EQFEDYGHMR F

Uniprot No.

P85852

Target Background

Function

Myotropic peptide.

Protein Families

Gastrin/cholecystokinin family

Subcellular Location

Secreted.

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Recombinant Elliptorhina sp. Sulfakinin-1

Description

Introduction to Recombinant Elliptorhina sp. Sulfakinin-1

Notes:

Table 2: Functional Roles of Sulfakinins in Insects

Key Mechanisms:

Applications in Research

Limitations and Future Directions

Product Specs

Target Background

Quick Inquiry

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