Recombinant Frog virus 3 Uncharacterized protein 040R (FV3-040R)
Description
Introduction to Recombinant Frog Virus 3 Uncharacterized Protein 040R (FV3-040R)
Recombinant Frog Virus 3 Uncharacterized Protein 040R (FV3-040R) is a protein derived from the Frog Virus 3 (FV3), a member of the Iridoviridae family. FV3 is well-studied for its role in understanding viral replication and transcription. Despite extensive research on FV3, many of its proteins, including FV3-040R, remain uncharacterized in terms of their specific functions within the viral lifecycle.
Background on Frog Virus 3 (FV3)
Frog Virus 3 is the most characterized member of the Iridoviridae family, which includes viruses infecting ectothermic vertebrates. FV3 has been used as a model to study viral replication, transcription, and host-virus interactions. The virus contains a large genome ranging from 105 to 212 kbp, with FV3 specifically having a genome size of approximately 105-106 kbp. This genome encodes numerous open reading frames (ORFs), many of which are involved in viral replication and virulence but remain poorly understood .
Table 1: General Characteristics of FV3 and Related Proteins
| Characteristic | Description |
|---|---|
| Virus Family | Iridoviridae |
| Genome Size | Approximately 105-106 kbp for FV3 |
| Number of ORFs | Between 92 and 139 for ranaviruses |
| Protein Function | Uncharacterized for FV3-040R |
| Research Use | Recombinant proteins used for studying viral mechanisms |
Research Findings and Applications
Research on FV3 proteins, including uncharacterized ones like FV3-040R, often involves molecular biology techniques such as knockdown and knockout experiments to elucidate their roles in viral replication and pathogenesis. These studies contribute to understanding viral-host interactions and may provide insights into developing antiviral strategies or biotechnological tools.
Table 2: Molecular Techniques Used in FV3 Research
| Technique | Description |
|---|---|
| Knockdown | Using antisense morpholino oligonucleotides (asMO) or siRNA to reduce protein expression |
| Knockout | Replacing targeted genes with selectable markers via homologous recombination |
| Ectopic Expression | Overexpressing viral genes in host cells to study their functions |
References:
- The Molecular Biology of Frog Virus 3 and other Iridoviruses.
- Uncharacterized protein 040R - Frog virus 3 (isolate Goorha) (FV-3).
- Recombinant Frog virus 3 Uncharacterized protein 004R(FV3-004R).
Product Specs
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Note: Our proteins are shipped with standard blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.
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