Recombinant Gecko japonicus Peroxiredoxin-1 (PRDX1)

Shipped with Ice Packs
In Stock

Product Specs

Form
Lyophilized powder
Note: We will prioritize shipping the format currently in stock. If you require a specific format, please specify this in your order notes.
Lead Time
Delivery times vary depending on the purchasing method and location. Please consult your local distributor for precise delivery estimates.
Note: All proteins are shipped with standard blue ice packs unless otherwise specified. Dry ice shipping requires prior arrangement and incurs additional charges.
Notes
Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.
Reconstitution
Centrifuge the vial briefly before opening to collect the contents. Reconstitute the protein in sterile, deionized water to a concentration of 0.1-1.0 mg/mL. We recommend adding 5-50% glycerol (final concentration) and aliquoting for long-term storage at -20°C/-80°C. Our standard glycerol concentration is 50% and can serve as a reference.
Shelf Life
Shelf life depends on various factors, including storage conditions, buffer composition, temperature, and the protein's inherent stability. Generally, liquid formulations have a 6-month shelf life at -20°C/-80°C, while lyophilized forms have a 12-month shelf life at -20°C/-80°C.
Storage Condition
Upon receipt, store at -20°C/-80°C. Aliquoting is essential for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
Tag type is determined during the manufacturing process.
The tag type is determined during production. If you require a specific tag, please inform us, and we will prioritize its development.
Synonyms
PRDX1; GekBS014P; Peroxiredoxin-1; EC 1.11.1.15
Buffer Before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Datasheet
Please contact us to get it.
Expression Region
1-199
Protein Length
full length protein
Purity
>85% (SDS-PAGE)
Species
Gekko japonicus (Schlegel's Japanese gecko)
Target Names
Target Protein Sequence
MSSGNAYIGK LAPDFQATAV MPDGQFKEIK LSDYKGKYVV LFFYPLDFTF VCPTEIIAFS DRSEEFRKIN CEVIGASVDS HFCHLAWINT PKKQGGLGSM HIPLVSDTKR VIAKDYGILK EDEGISYRGL FIIDDKGTLR QITINDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWQPG SDTIKPDVQK SKEYFSKHK
Uniprot No.

Target Background

Function
Thiol-specific peroxidase catalyzing the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. It plays a crucial role in cellular protection against oxidative stress by detoxifying peroxides and acting as a hydrogen peroxide-mediated signaling sensor. It may participate in growth factor and tumor necrosis factor-alpha signaling cascades by regulating intracellular H₂O₂ concentrations. Furthermore, it reduces an intramolecular disulfide bond in GDPD5, influencing GDPD5's ability to drive postmitotic motor neuron differentiation.
Protein Families
Peroxiredoxin family, AhpC/Prx1 subfamily
Subcellular Location
Cytoplasm.

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