Recombinant Haemophilus influenzae Uncharacterized protein HI_0850 (HI_0850)
Description
Understanding Recombinant Proteins
Recombinant proteins are produced through genetic engineering, where the gene encoding the protein is inserted into a host organism, such as Escherichia coli (E. coli), to express the protein. This technique allows for large-scale production of proteins for research, therapeutic, and diagnostic purposes.
Characteristics of Recombinant Proteins
-
Expression Host: Typically, E. coli is used for expressing recombinant proteins due to its well-understood genetics and ease of manipulation.
-
Purification: Recombinant proteins are often purified using techniques like affinity chromatography, especially when tagged with sequences like His-tags.
-
Applications: These proteins are used in research to study protein function, in diagnostics to detect diseases, and in therapeutics as vaccines or drugs.
Research on Haemophilus influenzae Proteins
While specific data on HI_0850 is not available, research on other Haemophilus influenzae proteins highlights the importance of understanding bacterial pathogenesis. For example, proteins like Haemophilus influenzae protein E (PE) play crucial roles in adhesion and immune evasion . Additionally, tools like the pTBH plasmid toolkit have been developed to study H. influenzae infection dynamics .
Challenges in Studying Haemophilus influenzae
-
Genetic Diversity: H. influenzae exhibits significant genetic diversity, making it challenging to develop universal diagnostic and therapeutic strategies .
-
Recombination: Frequent genetic recombination with other Haemophilus species complicates species identification and study .
Potential Applications of Recombinant Proteins
Recombinant proteins can be used to develop vaccines, diagnostic tools, and therapeutic agents. For instance, recombinant porins from H. influenzae have been studied for their pore-forming properties .
Data Table: Example of Recombinant Haemophilus influenzae Protein Characteristics
| Protein | Source | Tag | Length | Form | Purity |
|---|---|---|---|---|---|
| HI_0870.1 | E. coli | His | Full Length (1-96) | Lyophilized powder | >90% |
| HI_0234 | E. coli | Variable | Full Length (1-48) | Liquid/Lyophilized | >85% |
Note: The table provides characteristics of similar recombinant proteins from Haemophilus influenzae for reference.
Product Specs
Note: While we prioritize shipping the format currently in stock, please specify your format preference during order placement for customized preparation.
Note: All proteins are shipped with standard blue ice packs unless dry ice shipping is requested. Please contact us in advance to arrange dry ice shipment, as additional fees will apply.
If you require a specific tag type, please inform us; we will prioritize its development for your order.
Target Background
KEGG: hin:HI0850
STRING: 71421.HI0850
