Recombinant Human Transcription factor AP-2-delta (TFAP2D)

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Cat. No.
BT2459911
Source
Yeast
Synonyms
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta
Purity
>85% (SDS-PAGE)
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Cat. No.
BT2459911
Source
E.coli
Synonyms
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta
Purity
>85% (SDS-PAGE)
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Cat. No.
BT2459911
Source
E.coli
Synonyms
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta
Purity
>85% (SDS-PAGE)
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Cat. No.
BT2459911
Source
Baculovirus
Synonyms
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta
Purity
>85% (SDS-PAGE)
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Cat. No.
BT2459911
Source
Mammalian cell
Synonyms
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta
Purity
>85% (SDS-PAGE)
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Product Specs

Form
Lyophilized powder
Note: While we prioritize shipping the format currently in stock, please specify your format preference in order notes for customized preparation.
Lead Time
Delivery times vary depending on the purchase method and location. Please contact your local distributor for precise delivery estimates.
Note: All proteins are shipped with standard blue ice packs unless dry ice is requested in advance. Additional fees apply for dry ice shipping.
Notes
Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.
Reconstitution
Centrifuge the vial briefly before opening to collect the contents. Reconstitute the protein in sterile, deionized water to a concentration of 0.1-1.0 mg/mL. We recommend adding 5-50% glycerol (final concentration) and aliquoting for long-term storage at -20°C/-80°C. Our standard glycerol concentration is 50% and can serve as a guideline.
Shelf Life
Shelf life depends on various factors, including storage conditions, buffer composition, temperature, and protein stability. Generally, liquid formulations have a 6-month shelf life at -20°C/-80°C, while lyophilized forms have a 12-month shelf life at -20°C/-80°C.
Storage Condition
Upon receipt, store at -20°C/-80°C. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
Tag type is determined during the manufacturing process.
The tag type will be determined during production. Please specify your required tag type for preferential development.
Synonyms
activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta
Buffer Before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Datasheet
Please contact us to get it.
Expression Region
1-452
Protein Length
full length protein
Purity
>85% (SDS-PAGE)
Species
Homo sapiens (Human)
Target Names
TFAP2D
Target Protein Sequence
MSTTFPGLVH DAEIRHDGSN SYRLMQLGCL ESVANSTVAY SSSSPLTYST TGTEFASPYF STNHQYTPLH HQSFHYEFQH SHPAVTPDAY SLNSLHHSQQ YYQQIHHGEP TDFINLHNAR ALKSSCLDEQ RRELGCLDAY RRHDLSLMSH GSQYGMHPDQ RLLPGPSLGL AAAGADDLQG SVEAQCGLVL NGQGGVIRRG GTCVVNPTDL FCSVPGRLSL LSSTSKYKVT IAEVKRRLSP PECLNASLLG GILRRAKSKN GGRCLREKLD RLGLNLPAGR RKAANVTLLT SLVEGEALHL ARDFGYTCET EFPAKAVGEH LARQHMEQKE QTARKKMILA TKQICKEFQD LLSQDRSPLG SSRPTPILDL DIQRHLTHFS LITHGFGTPA ICAALSTFQT VLSEMLNYLE KHTTHKNGGA ADSGQGHANS EKAPLRKTSE AAVKEGKTEK TD
Uniprot No.
Q7Z6R9

Target Background

Function
Recombinant Human Transcription factor AP-2-delta (TFAP2D) is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate gene transcription. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in crucial biological processes, including development of the eye, face, body wall, limbs, and neural tube. They also repress genes such as MCAM/MUC18, C/EBP alpha, and MYC.
Gene References Into Functions
  1. Ap-2delta functions as a novel activating transcription factor for HMOX1. PMID: 24789576
  2. A novel human transcription factor AP-2-like gene (TFAP2BL1) has been cloned and characterized; it is located on human chromosome 6p12.1-21.1. PMID: 11733187
  3. AP-2epsilon and Ets-1 play a role in regulating integrin alpha10 transcription in chondrocytes. PMID: 16684505
Database Links

HGNC: 15581

OMIM: 610161

KEGG: hsa:83741

STRING: 9606.ENSP00000008391

UniGene: Hs.434107

Protein Families
AP-2 family
Subcellular Location
Nucleus.
Tissue Specificity
Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas.

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