Recombinant Macrothele gigas Delta-hexatoxin-Mg1a

Shipped with Ice Packs
In Stock

Product Specs

Form
Lyophilized powder. We will preferentially ship the available format. If you have specific format requirements, please note them when ordering, and we will accommodate your request.
Lead Time
Delivery times vary depending on purchasing method and location. Consult your local distributor for specific delivery information. All proteins are shipped with standard blue ice packs. For dry ice shipping, please contact us in advance, as extra fees will apply.
Notes
Avoid repeated freezing and thawing. Working aliquots can be stored at 4°C for up to one week.
Reconstitution
Briefly centrifuge the vial before opening to collect contents at the bottom. Reconstitute the protein in sterile deionized water to a concentration of 0.1-1.0 mg/mL. Adding 5-50% glycerol (final concentration) and aliquoting is recommended for long-term storage at -20°C/-80°C. Our default final glycerol concentration is 50% for your reference.
Shelf Life
Shelf life depends on several factors including storage conditions, buffer components, storage temperature, and protein stability. Generally, the liquid form has a shelf life of 6 months at -20°C/-80°C, while the lyophilized form is stable for 12 months at -20°C/-80°C.
Storage Condition
Store at -20°C/-80°C upon receiving. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
The tag type is determined during the manufacturing process. If you require a specific tag, please inform us, and we will prioritize developing it.
Synonyms
; Delta-hexatoxin-Mg1a; Delta-HXTX-Mg1a; Neurotoxin magi-4
Buffer Before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Datasheet
Please contact us to get it.
Expression Region
63-105
Protein Length
Cytoplasmic domain
Purity
>85% (SDS-PAGE)
Species
Macrothele gigas (Spider)
Target Protein Sequence
CGSKRAWC KEKKDCCCGY NCVYAWYNQQ SSCERKWKYL FTGEC
Uniprot No.

Target Background

Function
Selectively slows channel inactivation of mammalian Nav1.1/SCN1A, Nav1.3/SCN3A, and Nav1.6/SCN8A. It exhibits higher affinity for insect Nav1/para channels (site 3) and induces tonic repetitive firing of nerve impulses in insect neurons, accompanied by plateau potentials.
Protein Families
Delta-atracotoxin family
Subcellular Location
Secreted.
Tissue Specificity
Expressed by the venom gland.

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