Recombinant Methanocaldococcus jannaschii uncharacterized protein MJ1188 refers to a protein encoded by the gene MJ1188 in the hyperthermophilic archaeon Methanocaldococcus jannaschii. Despite being one of the earliest archaeal genomes sequenced, a significant portion of its genome, including the function of MJ1188, remains uncharacterized . This article aims to provide an overview of what is known about MJ1188 and the broader context of protein research in M. jannaschii.
Methanocaldococcus jannaschii is a deeply rooted hyperthermophilic methanarchaeon, with its genome being the first archaeal genome sequenced in 1996 . It is known for its ability to thrive in extreme environments, making it a subject of interest for studying extremophilic life forms and their metabolic pathways. The organism's genome encodes for numerous enzymes involved in methanogenesis and other metabolic processes .
Future studies on MJ1188 could involve:
Bioinformatics Analysis: Utilizing computational tools to predict potential functions based on sequence alignments and structural modeling.
Experimental Techniques: Employing recombinant DNA technology to express MJ1188 in a suitable host organism for functional analysis.
Proteomic Studies: Integrating MJ1188 into broader proteomic analyses to understand its interactions with other proteins within M. jannaschii.
| Category | Description | Number |
|---|---|---|
| Genome Size | Total base pairs | Not specified |
| Protein-Coding Genes | Total number of genes | Over 1,700 |
| Enzymes/Transporters | Predicted enzymatic activities | 540 |
| Metabolic Pathways | Inferred pathways | 142 |
| Uncharacterized Genes | Genes without known function | Over a third of the genome |
Note: Specific data for MJ1188 is not included due to its uncharacterized status.