Recombinant Methanothermobacter thermautotrophicus Uncharacterized protein MTH_137 (MTH_137)
Description
Biological Relevance
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MTH_137 is cataloged in the M. thermautotrophicus genome, which encodes ~1,869 protein genes involved in hydrogenotrophic methanogenesis .
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Proteomic studies of M. thermautotrophicus highlight dynamic membrane lipid composition under energy stress , though MTH_137’s role in these processes remains unconfirmed.
Experimental Use Cases
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Structural Studies: Recombinant MTH_137 is utilized in ELISA-based assays to explore antigen-antibody interactions, likely due to its stability in thermophilic conditions .
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Hypothesis-Driven Research: The protein’s uncharacterized status positions it as a candidate for investigating novel metabolic or regulatory pathways in archaea .
Genomic and Proteomic Associations
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Operon Context: MTH_137 resides in a genomic region with genes linked to membrane-associated processes, though direct functional linkages are unverified .
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Protein Complexes: M. thermautotrophicus expresses energy-generating complexes (e.g., methyltransferase and ATP synthase) , but MTH_137 has not been identified in these assemblies.
Limitations and Research Gaps
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Functional Annotation: No direct enzymatic or structural data for MTH_137 exists in public databases or literature.
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Regulatory Mechanisms: The protein’s expression profile during growth phases or stress (e.g., hydrogen limitation) is undocumented .
Future Directions
Product Specs
Note: While we prioritize shipping the format currently in stock, please specify your format preference during order placement for customized preparation.
Note: All proteins are shipped with standard blue ice packs. Dry ice shipping requires advance notification and incurs additional charges.
The tag type is determined during production. If a specific tag is required, please inform us, and we will prioritize its development.
Target Background
KEGG: mth:MTH_137
STRING: 187420.MTH137
