Recombinant Mouse Carbohydrate sulfotransferase 8 (Chst8), partial
Shipped with Ice Packs 
In Stock 
Product Specs
Form
Lyophilized powder
Note: While we will prioritize shipping the format currently in stock, please specify your format preference in order notes for customized preparation.
Note: While we will prioritize shipping the format currently in stock, please specify your format preference in order notes for customized preparation.
Lead Time
Delivery times vary depending on the purchase method and location. Please contact your local distributor for precise delivery estimates.
Note: All proteins are shipped with standard blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.
Note: All proteins are shipped with standard blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.
Notes
Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.
Reconstitution
Centrifuge the vial briefly before opening to collect the contents. Reconstitute the protein in sterile, deionized water to a concentration of 0.1-1.0 mg/mL. For long-term storage, we recommend adding 5-50% glycerol (final concentration) and aliquoting at -20°C/-80°C. Our default glycerol concentration is 50% and can serve as a reference.
Shelf Life
Shelf life depends on storage conditions, buffer composition, temperature, and protein stability. Generally, liquid formulations have a 6-month shelf life at -20°C/-80°C, while lyophilized formulations have a 12-month shelf life at -20°C/-80°C.
Storage Condition
Store at -20°C/-80°C upon receipt. Aliquot for multiple uses to prevent repeated freeze-thaw cycles.
Tag Info
Tag type is determined during manufacturing.
The specific tag type is determined during production. Please specify your desired tag type for prioritized development.
The specific tag type is determined during production. Please specify your desired tag type for prioritized development.
Synonyms
Chst8; Carbohydrate sulfotransferase 8; EC 2.8.2.-; GalNAc-4-O-sulfotransferase 1; GalNAc-4-ST1; GalNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1
Buffer Before Lyophilization
Tris/PBS-based buffer, 6%
Trehalose.
Datasheet
Please contact us to get it.
Protein Length
Partial
Purity
>85% (SDS-PAGE)
Species
Mus musculus (Mouse)
Target Names
Chst8
Uniprot No.
Target Background
Function
Carbohydrate sulfotransferase 8 (Chst8) catalyzes the transfer of sulfate to the 4-position of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It's essential for the biosynthesis of glycoprotein hormones lutropin and thyrotropin, mediating sulfation of their carbohydrate structures. Chst8 exhibits activity only against terminal GalNAcβ1, GalNAcβ and lacks activity toward chondroitin.
Gene References Into Functions
- Chst8 transcript levels influence the glycosaminoglycan environment of cellular prion protein, affecting its conversion to PrPSc. PMID: 21982770
- Enzymatic properties and expression analysis of GalNAc-4-sulfotransferase-1 and GalNAc-4-sulfotransferase-2. PMID: 16079414
Database Links
Protein Families
Sulfotransferase 2 family
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Tissue Specificity
Strongly expressed in brain. Weakly expressed in lung and kidney. Weakly expressed in pituitary.
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