Recombinant Mouse Zinc finger MYND domain-containing protein 15 (Zmynd15)

Shipped with Ice Packs
In Stock

Product Specs

Form
Lyophilized powder
Note: While we will prioritize shipping the format currently in stock, please specify your format preference in order notes; we will accommodate your request if possible.
Lead Time
Delivery times vary depending on the purchase method and location. Please contact your local distributor for precise delivery estimates.
Note: All proteins are shipped with standard blue ice packs unless otherwise requested. Dry ice shipping requires prior arrangement and incurs additional charges.
Notes
Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.
Reconstitution
Centrifuge the vial briefly before opening to collect the contents. Reconstitute the protein in sterile, deionized water to a concentration of 0.1-1.0 mg/mL. For long-term storage, we recommend adding 5-50% glycerol (final concentration) and aliquoting at -20°C/-80°C. Our standard glycerol concentration is 50% and can be used as a reference.
Shelf Life
Shelf life depends on several factors including storage conditions, buffer composition, temperature, and protein stability. Generally, liquid formulations have a 6-month shelf life at -20°C/-80°C, while lyophilized forms have a 12-month shelf life at -20°C/-80°C.
Storage Condition
Upon receipt, store at -20°C/-80°C. Aliquoting is essential for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
Tag type is determined during manufacturing.
The tag type is determined during production. If you require a specific tag, please inform us; we will prioritize its development.
Synonyms
Zmynd15; Zinc finger MYND domain-containing protein 15
Buffer Before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Datasheet
Please contact us to get it.
Expression Region
1-736
Protein Length
full length protein
Purity
>85% (SDS-PAGE)
Species
Mus musculus (Mouse)
Target Names
Zmynd15
Target Protein Sequence
MEFVSGYRDE FLDFAALLFG WFRKFVAERG TMGTSLEGRW RQLESQIRRL PQDPALWVLH VLPNRSVGIS LGQGAEPGPG PGLGASRLLG DEPPLHLRDL SPYVSFVSLE DGEEGEEEEE DEEHGERPGM EKVEPQEGGE PAPPSKRFPQ EAKPAPESEV TQQEASREEG SREERPEDER APEKRKGQKN AEAAPLHLSC LLLVTDEHGT ILGIDLLMDG AQGSVGQNPG TENLAPRAYA LLCHSMACPM GSGDPRKPRQ LTVGDAHLHR ELESLVPRLG VKLAKTPMRT WGPRPGFTFA SLRARTCHVC HKHSFEVKLT PCPQCSAVLY CGEACLQADW RRCPDDVSHR FWCPRLSAFM ERVGELASLP FTYTAEVTSE TFNKEAFLAS RGLTRGYWTQ LSMLIPGPGA PRYPWGSTSS LSCLLNGDPY QLLQGDGPAL MPPVPLEPPR SLFGSWQDYY TWRGLSLDSP MAVLLTYPLT VYYVITHLVP QSFPELNIQN KQSLKIHVVE AGKEFDLVMV FWELLVLLPH VALELQFVGD SLPPESDQQH FTMQRDGPEV SLRPGSGVSA RFNSGTKEKG GRRDLQIRVS ARPYHLLQGP KPDLVIGFNS GFGLKDTWLS SLPRLQSLRV PAFFTESSEY GCVMDDQTMA VATGGGTSSP QPNPFRSPFR LRAADNCMPW YCNAFIFHLV YKPPQGGTVR SAPGPAPRPP TPAAPPVPAR RRRGEKKAAR GPRRRR
Uniprot No.

Target Background

Function
Acts as a transcriptional repressor by interacting with histone deacetylases (HDACs). May regulate haploid genes crucial for spermiogenesis.
Gene References Into Functions
  1. ZMYND15 is the first identified transcriptional repressor essential for sperm production and male fertility. PMID: 20675388
Database Links

KEGG: mmu:574428

UniGene: Mm.425692

Subcellular Location
Nucleus. Cytoplasm. Note=In step 9-11 spermatids, shifts from nucleus to cytoplasm.
Tissue Specificity
Testis-specific. Expressed in pachytene spermatocytes and all developing spermatids, but not in Sertoli, nor Leydig cells (at protein level).

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