Recombinant Mouse Zinc finger protein OZF (Znf146)
Description
Introduction to Recombinant Mouse Zinc Finger Protein OZF (ZNF146)
Recombinant Mouse Zinc Finger Protein OZF (ZNF146) is a genetically engineered protein derived from the mouse homolog of the human ZNF146 gene. This protein belongs to the zinc finger protein family, which plays crucial roles in DNA binding, transcription regulation, and other cellular processes. The recombinant form of ZNF146 is produced using various expression systems, such as mammalian cells or bacterial systems, to facilitate research and potential therapeutic applications.
Structure and Function
Zinc finger proteins, including ZNF146, are characterized by their zinc finger domains, which are compact structures that bind zinc ions and facilitate interactions with DNA or RNA. These proteins are essential for regulating gene expression by binding to specific DNA sequences, thereby influencing transcriptional activity. The recombinant mouse ZNF146 protein retains these functional capabilities, making it useful for studying transcriptional regulation and related biological processes.
Production and Availability
Recombinant Mouse Zinc Finger Protein OZF (ZNF146) is available in various forms, including His-tagged and Myc/DDK-tagged versions, which are produced in mammalian cells like HEK293. These tags facilitate purification and detection of the protein in experimental settings. The protein is commercially available from several suppliers, offering researchers a range of options for their studies.
| Product Name | Source (Host) | Species | Tag | Protein Length |
|---|---|---|---|---|
| ZFP146-18834M | Mammalian Cells | Mouse | His | Not specified |
| Zfp146-7077M | HEK293 | Mouse | DDK & Myc | Not specified |
| ZNF146-10401M | HEK293 | Mouse | Avi & Fc & His | Not specified |
Transcriptional Regulation
ZNF146, like other zinc finger proteins, is predicted to be involved in the regulation of transcription by RNA polymerase II. This function is crucial for controlling gene expression and may be relevant in various biological contexts, including development and disease.
Neurological Implications
Although ZNF146 has not been directly linked to neurological diseases, zinc finger proteins in general play significant roles in neurogenesis and neurological disorders. The study of ZNF146 could provide insights into broader mechanisms of zinc finger proteins in the nervous system.
Product Specs
Note: While we prioritize shipping the format currently in stock, please specify your preferred format in order notes for customized preparation.
Note: All proteins are shipped with standard blue ice packs. Dry ice shipping requires advance notice and incurs additional charges.
The specific tag type is determined during production. If you require a particular tag, please specify it in your order for prioritized development.
