Recombinant Pelobacter propionicus Large-conductance mechanosensitive channel (mscL)
Description
Introduction to Recombinant Pelobacter propionicus Large-conductance Mechanosensitive Channel (mscL)
The Recombinant Pelobacter propionicus Large-conductance mechanosensitive channel (mscL) is a protein of interest in microbiological research, particularly in the study of mechanosensitive channels. Mechanosensitive channels are crucial for maintaining cellular osmotic balance by allowing ions to flow out of the cell when it is subjected to mechanical stress, such as changes in osmotic pressure. These channels are essential for the survival of bacteria in varying environments.
Background on Pelobacter propionicus
Pelobacter propionicus is a strictly anaerobic bacterium belonging to the family Geobacteraceae. It is known for its ability to ferment various organic compounds, producing propionate as a major end product . The study of its genetic components, such as the mscL channel, provides insights into how these bacteria adapt to different environmental conditions.
Mechanosensitive Channels
Mechanosensitive channels are membrane proteins that open in response to mechanical stress, allowing ions to flow out of the cell to prevent lysis. The large-conductance mechanosensitive channel (mscL) is one of the most studied mechanosensitive channels, originally identified in Escherichia coli. It is known for its large conductance and its role in protecting bacteria from osmotic shock.
Recombinant Pelobacter propionicus mscL
The recombinant form of the Pelobacter propionicus mscL channel is produced through genetic engineering techniques, where the gene encoding the mscL protein is cloned and expressed in a suitable host organism. This allows for the purification and study of the channel's properties in a controlled environment.
Data Tables
| Property | Description |
|---|---|
| Conductance | Large conductance, allowing rapid ion efflux. |
| Activation | Opens in response to mechanical stress (e.g., osmotic shock). |
| Function | Protects bacteria from lysis by releasing ions under osmotic stress. |
| Expression | Can be recombinantly expressed in various host organisms for study. |
References
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ELISA Recombinant Pelobacter propionicus Large-conductance mechanosensitive channel(mscL): This product is available for research purposes but lacks detailed scientific publications specifically on its properties and functions .
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Pelobacter propionicus: Known for its anaerobic metabolism and propionate production, this bacterium's genetic components, like the mscL channel, are of interest for understanding microbial adaptation .
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Mechanosensitive Channels: General studies on mscL channels highlight their role in bacterial survival under osmotic stress, providing a framework for understanding similar channels in other bacteria.
Product Specs
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Target Background
KEGG: ppd:Ppro_1689
STRING: 338966.Ppro_1689
