Recombinant Phoneutria nigriventer U7-ctenitoxin-Pn1a

Shipped with Ice Packs
In Stock

Product Specs

Form
Lyophilized powder. We will ship the in-stock format unless you specify a format preference when ordering.
Lead Time
Delivery times vary by purchase method and location. Consult local distributors for specifics. Proteins are shipped with blue ice packs. Request dry ice in advance for an extra fee.
Notes
Avoid repeated freezing and thawing. Store working aliquots at 4°C for up to one week.
Reconstitution
Briefly centrifuge the vial before opening. Reconstitute in sterile deionized water to 0.1-1.0 mg/mL. Add 5-50% glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default glycerol concentration is 50%.
Shelf Life
Shelf life depends on storage conditions, buffer, temperature, and protein stability. Liquid form: 6 months at -20°C/-80°C. Lyophilized form: 12 months at -20°C/-80°C.
Storage Condition
Store at -20°C/-80°C upon receipt. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
Tag type is determined during manufacturing. If you require a specific tag, inform us, and we will prioritize its development.
Synonyms
; U7-ctenitoxin-Pn1a; U7-CNTX-Pn1a; Neurotoxin Tx3-5; PnTx3-5
Buffer Before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Datasheet
Please contact us to get it.
Expression Region
40-84
Protein Length
Full Length of Mature Protein
Purity
>85% (SDS-PAGE)
Species
Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer)
Target Protein Sequence
G CIGRNESCKF DRHGCCWPWS CSCWNKEGQP ESDVWCECSL KIGK
Uniprot No.

Target Background

Function
Antagonist of L-type calcium channels (Cav1/CACNA1). In mice, a 5µg dose causes hind limb paralysis and reduced movement/aggression within 24 hours.
Protein Families
Plectoxin superfamily, Tx3 family
Subcellular Location
Secreted.
Tissue Specificity
Expressed by the venom gland.

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