Recombinant Princisia vanwaerbeki Periviscerokinin-3

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Cat. No.

BT46278

Source

Yeast

Synonyms

Periviscerokinin-3; PriVa-PVK-3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT46278

Source

E.coli

Synonyms

Periviscerokinin-3; PriVa-PVK-3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT46278

Source

E.coli

Synonyms

Periviscerokinin-3; PriVa-PVK-3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT46278

Source

Baculovirus

Synonyms

Periviscerokinin-3; PriVa-PVK-3

Purity

>85% (SDS-PAGE)

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Cat. No.

BT46278

Source

Mammalian cell

Synonyms

Periviscerokinin-3; PriVa-PVK-3

Purity

>85% (SDS-PAGE)

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Description

Comparative Analysis of PVK Homologs

PVKs exhibit sequence and functional conservation across arthropods:

Species	PVK Type	Sequence	Key Function
Princisia vanwaerbeki	PVK-3	GSSGLISMPRV	Visceral muscle contraction
Pilema dubia	PVK-3	GSSGMIPFPRV	Myotropic activity in cockroaches
Periplaneta americana	PVK-1	GASGLIPVMRN-NH₂	Hyperneural muscle excitation
Rhipicephalus microplus	CAP2b/PVK	pQGLIPFPRVa	Female feeding, reproduction, and survival

4.1. In Vitro Studies

PriVa-PVK-3 is used to investigate:

Muscle Contraction Mechanisms: Testing dose-dependent responses in insect visceral tissues .
Receptor Binding: Mapping interactions with G-protein-coupled receptors (GPCRs) in arthropods .

4.2. Physiological Impact

Silencing PVK receptors in R. microplus reduced female survival (28% mortality), egg mass weight (20–30% decrease), and egg hatching rates (15–20% decline) , highlighting PVKs as potential targets for pest control.

Knowledge Gaps and Future Directions

Structural-Activity Relationships (SAR): Limited data on PriVa-PVK-3’s binding kinetics or receptor specificity.
In Vivo Efficacy: No published studies on its effects in Princisia vanwaerbeki or related species.
Therapeutic Potential: Antagonists of PVK signaling could disrupt arthropod physiology, offering novel pest-control strategies .

Product Specs

Form

Lyophilized powder. We preferentially ship the in-stock format. For specific format requirements, please note them when ordering.

Lead Time

Delivery times vary by purchase method and location. Consult local distributors for specific delivery times. All proteins are shipped with blue ice packs by default. Request dry ice in advance (extra fees apply).

Notes

Avoid repeated freezing and thawing. Store working aliquots at 4°C for up to one week.

Reconstitution

Briefly centrifuge the vial before opening. Reconstitute in sterile deionized water to 0.1-1.0 mg/mL. Add 5-50% glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final glycerol concentration is 50%.

Shelf Life

Shelf life depends on storage conditions, buffer ingredients, temperature, and protein stability. Liquid form: 6 months at -20°C/-80°C. Lyophilized form: 12 months at -20°C/-80°C.

Storage Condition

Store at -20°C/-80°C upon receipt. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.

Tag Info

Tag type is determined during manufacturing. If you require a specific tag, please inform us and we will prioritize its development.

Synonyms

Periviscerokinin-3; PriVa-PVK-3

Buffer Before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Datasheet

Please contact us to get it.

Expression Region

1-11

Protein Length

Cytoplasmic domain

Purity

>85% (SDS-PAGE)

Species

Princisia vanwaerebeki (Tiger hisser roach)

Target Protein Sequence

GSSGMIPFPR V

Uniprot No.

P85746

Target Background

Function

Mediates visceral muscle contractile activity (myotropic activity).

Protein Families

Periviscerokinin family

Subcellular Location

Secreted.

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Recombinant Princisia vanwaerbeki Periviscerokinin-3

Description

Comparative Analysis of PVK Homologs

4.1. In Vitro Studies

4.2. Physiological Impact

Knowledge Gaps and Future Directions

Product Specs

Target Background

Quick Inquiry

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Service