Recombinant proteins are proteins produced by cells engineered with a specific gene, serving as a vital tool in scientific research, diagnostics, and therapeutics . These proteins can have the same amino acid sequence as naturally occurring proteins or be modified for improved properties such as solubility or production yield .
The production of recombinant proteins involves several steps:
Generation of Recombinant DNA: This is achieved through molecular cloning or PCR (Polymerase Chain Reaction) .
Expression Systems: Once the recombinant DNA is prepared, it is introduced into a host expression system such as E. coli, yeast, or mammalian cells for protein production .
Recombinant proteins have numerous applications:
Therapeutics: Used in treating conditions like cancer, autoimmune diseases, and genetic disorders .
Research Tools: Employed in cell culture supplements, disease modeling, and drug discovery .
Diagnostic Antigens: Used for immunization and antibody production .
Since there is no specific data available for "Recombinant Protein spdB (spdB)", here is a general table summarizing types of recombinant proteins and their applications:
| Type of Recombinant Protein | Applications |
|---|---|
| Chemokines | Research, Therapeutics |
| Interferons | Therapeutics, Research |
| Colony Stimulating Factors | Therapeutics, Research |
| Growth Factors | Therapeutics, Research |
| Enzymes | Diagnostics, Therapeutics |
| Recombinant Antibodies | Diagnostics, Therapeutics |
Crown Bioscience Blog: Introduction to Recombinant Proteins
PJMONLINE: A Comparative Study on the Activity and Antigenicity of Truncated Streptokinase
Thermo Fisher Scientific: Recombinant Protein Information
PMC: Impact of Structural Biologists and the Protein Data Bank
Evitria: Recombinant Protein - Definition, Examples & Production