Recombinant Shigella boydii serotype 4 4-hydroxybenzoate octaprenyltransferase (ubiA)
Description
Introduction to Recombinant Shigella boydii Serotype 4 4-Hydroxybenzoate Octaprenyltransferase (ubiA)
Recombinant Shigella boydii serotype 4 4-hydroxybenzoate octaprenyltransferase (ubiA) is a recombinant protein derived from the ubiA gene of Shigella boydii serotype 4. This enzyme plays a crucial role in the biosynthesis of ubiquinone, a vital component of the electron transport chain in bacteria. The ubiA gene encodes for the enzyme responsible for the first committed step in ubiquinone biosynthesis, transferring a prenyl group from octaprenyl diphosphate to 4-hydroxybenzoate.
Function and Importance of 4-Hydroxybenzoate Octaprenyltransferase
4-Hydroxybenzoate octaprenyltransferase is essential for the synthesis of ubiquinone, which is crucial for the electron transport chain and ATP production in bacteria. This enzyme catalyzes the transfer of an octaprenyl group to 4-hydroxybenzoate, forming 3-octaprenyl-4-hydroxybenzoate, a key intermediate in the ubiquinone biosynthesis pathway.
Recombinant Protein Characteristics
The recombinant Shigella boydii serotype 4 4-hydroxybenzoate octaprenyltransferase (ubiA) is available as a recombinant protein product. Key characteristics include:
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Product Type: Recombinant Protein
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Species: Shigella boydii serotype 4 (strain Sb227)
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Uniprot Number: Q31TU8
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Tag Information: The tag type is determined during production.
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Storage Buffer: Tris-based buffer with 50% glycerol.
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Storage Conditions: Store at -20°C for short-term storage or -80°C for long-term storage .
Data Table: Characteristics of Recombinant Shigella boydii Serotype 4 4-Hydroxybenzoate Octaprenyltransferase
| Characteristics | Description |
|---|---|
| Product Type | Recombinant Protein |
| Species | Shigella boydii serotype 4 (strain Sb227) |
| Uniprot Number | Q31TU8 |
| Tag Information | Determined during production |
| Storage Buffer | Tris-based buffer with 50% glycerol |
| Storage Conditions | Store at -20°C or -80°C |
Product Specs
Note: While we prioritize shipping the format currently in stock, please specify your format preference in order notes for customized preparation.
Note: Standard shipping includes blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.
The tag type is determined during the production process. If a specific tag type is required, please inform us for preferential development.
Target Background
This enzyme catalyzes the prenylation of para-hydroxybenzoate (PHB) using an all-trans polyprenyl group. It mediates the second step in ubiquinone-8 (UQ-8) biosynthesis, specifically the condensation of the polyisoprenoid side chain with PHB, resulting in the formation of the initial membrane-bound Q intermediate, 3-octaprenyl-4-hydroxybenzoate.
KEGG: sbo:SBO_4077
