Recombinant Takifugu rubripes Mast/stem cell growth factor receptor Kit (kit), partial
Description
Introduction to Recombinant Takifugu rubripes Mast/stem cell growth factor receptor Kit (kit), partial
The Recombinant Takifugu rubripes Mast/stem cell growth factor receptor Kit (kit), partial refers to a genetically engineered version of the mast/stem cell growth factor receptor, also known as c-Kit, derived from the Japanese pufferfish, Takifugu rubripes. This receptor plays a crucial role in cell signaling pathways, particularly in the regulation of hematopoiesis and the development of various cell types. The term "partial" suggests that this recombinant protein may not include the full-length sequence of the native receptor.
Biological Significance of c-Kit
c-Kit is a receptor tyrosine kinase that binds to its ligand, stem cell factor (SCF), to initiate signaling cascades involved in cell proliferation, differentiation, and survival. In vertebrates, including fish like Takifugu rubripes, c-Kit is essential for the development and function of hematopoietic cells, melanocytes, and germ cells .
Recombinant Protein Production
Recombinant proteins are produced using genetic engineering techniques where the gene encoding the protein of interest is inserted into an expression vector and then expressed in a suitable host organism. For Takifugu rubripes c-Kit, this process would involve cloning the gene into a vector and expressing it in a system such as bacteria or mammalian cells.
Potential Applications
The recombinant Takifugu rubripes c-Kit could have several applications:
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Research Tool: It can be used to study the signaling pathways and biological functions of c-Kit in fish, providing insights into hematopoiesis and immune system development.
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Aquaculture: Understanding the role of c-Kit in fish could lead to improved health management strategies for farmed fish, enhancing their immune response and resilience to diseases.
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Biotechnology: The recombinant protein could serve as a model for studying receptor-ligand interactions and developing novel biotechnological products.
Data Tables
Given the lack of specific data on the recombinant Takifugu rubripes c-Kit, we can consider general characteristics of c-Kit and related proteins:
| Characteristics | Description |
|---|---|
| Protein Type | Receptor Tyrosine Kinase |
| Ligand | Stem Cell Factor (SCF) |
| Biological Role | Cell Proliferation, Differentiation, Survival |
| Species | Takifugu rubripes (Japanese Pufferfish) |
| Applications | Research, Aquaculture, Biotechnology |
Product Specs
Note: While we prioritize shipping the format currently in stock, please specify your format preference in order notes for customized preparation.
Note: All proteins are shipped with standard blue ice packs. Dry ice shipping requires prior arrangement and incurs additional charges.
The tag type is determined during production. If you require a specific tag, please inform us; we will prioritize its development.
Target Background
Recombinant Takifugu rubripes Mast/stem cell growth factor receptor Kit (kit), partial
A tyrosine-protein kinase functioning as a cell-surface receptor for the cytokine kitlg/scf. It plays a crucial role in regulating cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and melanogenesis.
KEGG: tru:101073765
STRING: 31033.ENSTRUP00000038813
