Recombinant Thermotoga petrophila Serine hydroxymethyltransferase (glyA)
Shipped with Ice Packs 
In Stock 
Product Specs
Form
Lyophilized powder. We will ship the format in stock, but if you have special format requirements, please note them when ordering, and we will fulfill your request.
Lead Time
Delivery times vary based on purchasing method and location. Consult your local distributor for specific delivery times. All proteins are shipped with blue ice packs by default. Request dry ice shipment in advance for an extra fee.
Notes
Avoid repeated freeze-thaw cycles. Store working aliquots at 4°C for up to one week.
Reconstitution
Briefly centrifuge the vial before opening to collect contents at the bottom. Reconstitute protein in sterile deionized water to 0.1-1.0 mg/mL. Add 5-50% glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final glycerol concentration is 50%.
Shelf Life
Shelf life depends on storage conditions, buffer ingredients, storage temperature, and protein stability. Liquid form shelf life is generally 6 months at -20°C/-80°C. Lyophilized form shelf life is generally 12 months at -20°C/-80°C.
Storage Condition
Store at -20°C/-80°C upon receipt. Aliquot for multiple uses. Avoid repeated freeze-thaw cycles.
Tag Info
The tag type is determined during manufacturing. If you require a specific tag, please inform us, and we will prioritize developing it.
Synonyms
glyA; Tpet_0209Serine hydroxymethyltransferase; SHMT; Serine methylase; EC 2.1.2.1
Buffer Before Lyophilization
Tris/PBS-based buffer, 6%
Trehalose.
Datasheet
Please contact us to get it.
Expression Region
1-427
Protein Length
full length protein
Purity
>85% (SDS-PAGE)
Species
Thermotoga petrophila (strain RKU-1 / ATCC BAA-488 / DSM 13995)
Target Names
glyA
Target Protein Sequence
MWKHVKQVDP EIYEVLVNEL KRQEYGLELI ASENFASLAV IETMGSMLTN KYAEGYPQKR
YYGGCEWVDR AEELAIERAK RLFGAKFANV QPHSGSQANM AVYLALAQPG DTIMGMSLSH
GGHLTHGAPV NFSGKIFKVV PYGVNLETET IDYDEVRRLA LEHKPKIIVA GGSAYARIID
FKRFREIADE VGAYLMVDMA HFAGLVAAGI HPNPLEYAHV VTSTTHKTLR GPRGGLILTN
DPDIAKAVDK TIFPGIQGGP LMHVIAAKAV CFKEAMTEEF KEYQKQVVKN AKKMAEEFQK
RGYRIVSGGT DTHLFLVDLT PKDITGKAAE KALESCGITV NKNTIPNEKR SPFVASGIRI
GTPAVTTRGM KEEEMEEIAE MIDLVLSNVT DENGTVKPEV REEVSKRVRE LCERFPLYRD
KIEGVEI
Uniprot No.
Target Background
Function
Catalyzes the reversible interconversion of serine and glycine, using tetrahydrofolate (THF) as the one-carbon carrier. This reaction is the primary source of one-carbon groups needed for biosynthesis of purines, thymidylate, methionine, and other biomolecules. Also exhibits THF-independent aldolase activity towards beta-hydroxyamino acids, producing glycine and aldehydes via a retro-aldol mechanism.
Database Links
KEGG: tpt:Tpet_0209
STRING: 390874.Tpet_0209
Protein Families
SHMT family
Subcellular Location
Cytoplasm.
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