Recombinant Ureaplasma parvum serovar 3 Uncharacterized protein UU041 (UU041)
Description
Overview of Ureaplasma parvum
Ureaplasma parvum (UPA) is a sexually transmitted bacterium implicated in disease states including infertility, nongonococcal urethritis, adverse pregnancy outcomes, chorioamnionitis, and bronchopulmonary dysplasia in neonates . There are four serovars of U. parvum . Determining the pathogenic potential at the ureaplasma serovar level has been difficult due to the limitations of antibody-based typing methods, multiple cross-reactions, and poor discriminating capacity in clinical samples containing multiple serovars .
General Information on UU041
The Ureaplasma parvum serovar 3 Uncharacterized protein UU041 (UU041) is a protein present in Ureaplasma parvum serovar 3. It is currently labeled as an uncharacterized protein, meaning its specific function and role within the organism are not yet fully understood. Research is ongoing to elucidate its properties and potential functions.
Genetic Context and Location
The gene encoding UU041 is located within the genome of U. parvum serovar 3. Comparative genome analysis of different Ureaplasma strains reveals genetic variations that may contribute to differences in their pathogenic potential .
Research on Tyrosine Recombinases in U. parvum serovar 3
Research has documented the presence of tyrosine recombinases (RipX, XerC, and CodV encoded by the genes UU145, UU222, and UU529) in the genome of U. parvum serovar 3, which could be mediators in the proposed recombination event . In vitro binding of recombinant maltose-binding protein fusions of XerC to the inverted repeats of the phase-variable loci, of RipX to a direct repeat that flanks a 20-kbp region, which has been proposed as putative pathogenicity island, and of CodV to a putative dif site has been demonstrated .
Product Specs
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Target Background
KEGG: uur:UU041
STRING: 273119.UU041
