Recombinant Xenopus laevis Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 1 (Ergic1) is a recombinant protein derived from the African clawed frog, Xenopus laevis. This protein is involved in the early secretory pathway, specifically within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC). The ERGIC plays a crucial role in the trafficking of proteins and lipids between the endoplasmic reticulum and the Golgi apparatus.
Ergic1 is a full-length protein consisting of 290 amino acids, expressed in Escherichia coli (E. coli) and fused with an N-terminal His tag for easy purification and detection . The protein is available in a lyophilized powder form with a purity of greater than 90% as determined by SDS-PAGE .
| Characteristics | Description |
|---|---|
| Species | Xenopus laevis |
| Source | E. coli |
| Tag | N-terminal His |
| Protein Length | Full Length (1-290aa) |
| Form | Lyophilized powder |
| Purity | >90% (SDS-PAGE) |
| Storage | -20°C/-80°C |
Research on Ergic1 and related proteins has provided insights into the mechanisms of protein trafficking and quality control within the early secretory pathway. These studies are crucial for understanding cellular processes and have implications for biotechnology and biomedical research. For instance, recombinant proteins like Ergic1 can be used in studies to elucidate the molecular mechanisms of protein transport and in the development of therapeutic proteins.
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KEGG: xla:431823
UniGene: Xl.30468