Recombinant Yersinia pseudotuberculosis serotype IB Protein AaeX (aaeX)
Description
Research Applications
AaeX is primarily used to study Yersinia pathogenesis and host immune responses.
3.1. Immunological Studies
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Antibody Development: Recombinant AaeX serves as an antigen for generating serotype-specific antibodies, aiding in diagnostic assays .
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ELISA: Quantitative detection of anti-AaeX antibodies in serum samples to assess immune responses .
3.2. Functional Analysis
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Cellular Assays: While direct evidence for AaeX’s role is limited, its homology to effector proteins suggests potential involvement in:
Comparative Analysis with Related Proteins
AaeX is distinct from other Yersinia virulence factors but shares structural or functional parallels with:
Challenges and Future Directions
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Functional Elucidation: Current research lacks direct evidence of AaeX’s role in Yersinia pathogenesis. Further studies are needed to:
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Identify host targets (e.g., integrins, Rho GTPases).
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Assess its contribution to bacterial survival or immune evasion.
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Diagnostic Potential: AaeX could be a biomarker for serotyping Y. pseudotuberculosis strains, though validation is required.
Product Specs
Note: We prioritize shipping the format currently in stock. However, if you have specific format requirements, please indicate them during order placement. We will accommodate your request whenever possible.
Note: All our proteins are shipped with standard blue ice packs. If you require dry ice shipping, please inform us in advance, as additional fees will apply.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Target Background
KEGG: ypb:YPTS_3734
