GLV1 Antibody
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In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
RGF6 antibody; At4g16515 antibody; FCAALL antibody; Root meristem growth factor 6 antibody; AtRGF6 antibody
Target Names
GLV1
Uniprot No.
Target Background
Function
GLV1 is a signaling peptide (root growth factor) that plays a crucial role in regulating root development. It modulates the pattern of root growth and lateral root development by influencing the size and number of cells in the root apical meristem (RAM), and the asymmetric cell divisions during lateral root initiation. Furthermore, GLV1 is involved in regulating hypocotyl bending and root gravitropism in a PIN2-dependent manner, thereby contributing to the formation of auxin gradients. Notably, GLV1 maintains the postembryonic root stem cell niche.
Gene References Into Functions
- The GLV1 precursor is a direct substrate of subtilase. Eliminating the in vitro subtilase recognition sites through alanine substitution effectively suppressed the GLV1 gain-of-function phenotype in vivo. The protease inhibitor Serpin1 binds to SBT6.1, inhibiting the cleavage of GLV1 precursors by the protease. PMID: 27315833
Database Links
Protein Families
RGF family
Subcellular Location
Endoplasmic reticulum.; [GLV1p]: Secreted.
Tissue Specificity
Expressed in stems, hypocotyls, cotyledons, leaves, flowers, shoot apex, siliques, stamens and petals.
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