RHM2 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
RHM2 antibody; MUM4 antibody; At1g53500 antibody; F22G10.13 antibody; T3F20.18 antibody; Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2 antibody; NDP-rhamnose synthase antibody; Protein MUCILAGE-MODIFIED 4 antibody; Protein RHAMNOSE BIOSYNTHESIS 2 antibody; Rhamnose biosynthetic enzyme 2 antibody; AtRHM2 antibody; UDP-L-rhamnose synthase MUM4) [Includes: UDP-glucose 4,6-dehydratase antibody; EC 4.2.1.76); UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose 4-keto-reductase antibody; EC 1.1.1.- antibody; EC 5.1.3.-)] antibody
Target Names
RHM2
Uniprot No.
Target Background
Function
RHM2 is a trifunctional enzyme that plays a critical role in UDP-beta-L-rhamnose biosynthesis. UDP-beta-L-rhamnose is a precursor for the primary cell wall components, rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II). RHM2 catalyzes three sequential reactions: dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose, epimerization of the C3' and C5' positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose, and reduction of UDP-4-keto-beta-L-rhamnose to yield UDP-beta-L-rhamnose. This enzyme is essential for normal seed coat epidermal development.
Gene References Into Functions
- RHM2 is found in both Arabidopsis and Camelina sativa, and its expression is regulated by the same transcription factor cascade as the endogenous MUM4 gene. PMID: 28730525
- The transcription factors GL2 and RHM2 are crucial for the biosynthesis of mucilage pectin. PMID: 22735692
- MUM4 is a target gene of GL2 in the seed coat, and GL2 regulates seed oil production at least partially through its influence on MUM4 expression in the seed coat. PMID: 21883555
Database Links
Protein Families
NAD(P)-dependent epimerase/dehydratase family, dTDP-glucose dehydratase subfamily; DTDP-4-dehydrorhamnose reductase family
Tissue Specificity
Expressed in roots, stems, leaves, seedlings, inflorescence tips, and siliques.
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