At2g25100 Antibody
Shipped with Ice Packs 
In Stock 
Product Specs
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
At2g25100 antibody; F13D4.60Ribonuclease H2 subunit A antibody; RNase H2 subunit A antibody; EC 3.1.26.4 antibody; Ribonuclease HI large subunit antibody; RNase HI large subunit antibody; Ribonuclease HI subunit A antibody
Target Names
At2g25100
Uniprot No.
Target Background
Function
The At2g25100 antibody targets the catalytic subunit of RNase HII, an endonuclease responsible for the specific degradation of RNA within RNA:DNA hybrids. This enzyme plays a crucial role in DNA replication, potentially by mediating the removal of lagging-strand Okazaki fragment RNA primers during this process. Additionally, it facilitates the excision of single ribonucleotides from DNA:RNA duplexes.
Gene References Into Functions
- Mutant alleles of genes encoding subunits of the ribonuclease H2 (RNase H2) complex, known for its role in removing ribonucleotides from DNA-RNA duplexes, were identified as suppressor mutants of WEE1 knockout plants. PMID: 25217508
Database Links
Protein Families
RNase HII family, Eukaryotic subfamily
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