slc39a10 Antibody
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Product Specs
Buffer
**Preservative:** 0.03% Proclin 300
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
**Constituents:** 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Lead Time
Made-to-order (14-16 weeks)
Synonyms
slc39a10 antibody; zip10 antibody; zgc:63552 antibody; Zinc transporter ZIP10 antibody; Solute carrier family 39 member 10 antibody; Zrt- and Irt-like protein 10 antibody; ZIP-10 antibody
Target Names
slc39a10
Uniprot No.
Target Background
Function
SLC39A10 (Solute Carrier Family 39 Member 10), also known as ZIP10, is a protein that in humans is encoded by the SLC39A10 gene. This protein may act as a zinc-influx transporter.
Gene References Into Functions
- Studies have shown that metal response elements can function as repressor elements, suggesting that MTF1 (Metal-Responsive Transcription Factor 1) is involved in the negative regulation of ZIP10. This finding was reported in a research paper published in 2008. [ZnT] PMID: 18477665
- Downregulation of ZnT1 (Zinc Transporter 1) and overexpression of ZIP10 in response to ovarian zinc depletion induced by cadmium (Cd) play a significant role in cadmium accumulation and subsequent reproductive toxicity. This was reported in a 2012 study. PMID: 21756885
- Further research supports the role of metal response elements as repressor elements, implicating MTF1 in the negative regulation of ZIP10. This evidence was presented in a 2008 publication. PMID: 18477665
Database Links
Protein Families
ZIP transporter (TC 2.A.5) family
Subcellular Location
Membrane; Multi-pass membrane protein.
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